Development of an artificial intelligence-derived histologic signature associated with adjuvant gemcitabine treatment outcomes in pancreatic cancer.

Pancreatic ductal adenocarcinoma (PDAC) has been left behind in the evolution of personalized medicine. Predictive markers of response to therapy are lacking in PDAC despite various histological and transcriptional classification schemes. We report an artificial intelligence (AI) approach to histologic feature examination that extracts a signature predictive of disease-specific survival (DSS) in patients with PDAC receiving adjuvant gemcitabine.

Non-Contact Type Pulse Oximeter.

Heart rate and through-body blood perfusion are vital measurements in all stages of patient care, be it predictive, in the clinical setting, or outpatient monitoring. Irregular, underachieving, or overperforming heart rate is the main precursor of most cardiovascular diseases that have severe long-term complications. In addition to heart rate, the shape of the pulse waveforms can indicate the heart's valve health and electrophysiology health.

SeismoWatch: Wearable Cuffless Blood Pressure Monitoring Using Pulse Transit Time.

The current norm for measuring blood pressure (BP) at home is using an automated BP cuff based on oscillometry. Despite providing a viable and familiar method of tracking BP at home, oscillometric devices can be both cumbersome and inaccurate with the inconvenience of the hardware typically limiting measurements to once or twice per day. To address these limitations, a wrist-watch BP monitor was developed to measure BP through a simple maneuver: holding the watch against the sternum to detect micro-vibrations of the chest wall associated with the heartbeat.