Anaplastic thyroid carcinoma with leucocytosis.

Background: Anaplastic thyroid carcinoma is a high-grade tumour with poor prognosis. Most of the cases are easily diagnosed on cytology and some of these are associated with increased neutrophils in cytology specimen as well as in the blood. The objective of the study is to determine the frequency of neutrophilia with fever in anaplastic thyroid carcinoma.

Leiomyoma: Its Variants And Secondary Changes A Five-Year Study.

Background: Abnormal uterine bleeding is a common problem encountered by the gynaecologists, leiomyoma being one of the most common causes. An accurate knowledge of the different variants and secondary changes occurring in leiomyoma is essential as some of these may mimic malignancy clinically, radiologically and histologically. Some important examples being atypical, cellular and mitotically active leiomyoma.

Immunohistochemical Analysis Of Breast Cancer Subtypes And Their Correlation With Ki 67 Index.

Background: Breast cancer is the second most common cancer in females including Pakistan. Nowadays immunohistochemistry has revolutionized management of breast cancer. In this study, we determined the frequency of various subtypes of breast cancer on the basis of immunohistochemical staining and their correlation with ki 67 index.

Effects of smoking on length of hospital stay in patients surviving an orthotopic liver transplant.

Background: Smoking in orthotopic liver transplant (OLT) recipients has been associated with increased risk of vascular complications, cardiac events, graft failure and oesophegeal cancer. The aim of this study was to determine the effect of smoking on length of hospital stay post OLT and also to audit support provided to these patients.

Methods: This was a retrospective study carried out in the Liver Transplant Unit, St James University Hospital, UK from 1979 to 2005.

Inflammatory markers and lipid profile in patients of coronary artery disease.

Background: Coronary artery diseases encompass a spectrum of disorders ranging from angina to fatal myocardial infarctions with the main underlying pathology being identified as atherosclerosis.

Methods: The level of inflammatory markers, C-reactive protein and fibrinogen was determined in hundred patients with established coronary artery disease and correlated with lipid profile which included serum cholesterol, high density lipoprotein (HDL), low density lipoprotein and triglycerides.

Results: The results showed a positive correlation between Inflammatory Marker CRP with LDL and serum cholesterol in patients with coronary artery disease.