Rocephin-graphene oxide-silver nanocomposites: A versatile platform for biomedical applications.

For many years, the synthesis of graphene oxide (GO) had involved exfoliating graphite flakes, and the methods applied were expensive and time-consuming. Thus, an attempt had been made to create an inventive, less expensive method for the synthesis of GO using unrefined, raw carbon-containing material. Modified Hummer's method was used to prepare GO from banana peel.

Biological Applications of Ball-Milled Synthesized Biochar-Zinc Oxide Nanocomposite Using L.

Nanotechnology is one of the vital and quickly developing areas and has several uses in various commercial zones. Among the various types of metal oxide-based nanoparticles, zinc oxide nanoparticles (ZnO NPs) are frequently used because of their effective properties. The ZnO nanocomposites are risk-free and biodegradable biopolymers, and they are widely being applied in the biomedical and therapeutics fields.

Synthesis of novel silica encapsulated spiropyran-based thermochromic materials.

A series of novel spiropyrans were synthesized through the condensation of substituted 3,3-dimethyl-2-methyleneindoline with different nitro-substituted -hydroxy aromatic aldehydes. Indoles were initially substituted with a variety of alkanes and esters moieties. The substituted 3,3-dimethyl-2-methyleneindoline was then reacted with nitro-substituted -hydroxy aromatic aldehydes to yield the respective spiropyrans.

Alpha-synuclein aggresomes inhibit ciliogenesis and multiple functions of the centrosome.

Protein aggregates are the pathogenic hallmarks of many different neurodegenerative diseases and include the accumulation of α-synuclein, the main component of Lewy bodies found in Parkinson's disease. Aggresomes are closely-related, cellular accumulations of misfolded proteins. They develop in a juxtanuclear position, adjacent to the centrosome, the microtubule organizing centre of the cell, and share some protein components.

Synthesis and characterization of DGEBA composites reinforced with Cu/Ag modified carbon nanotubes.

Carbon nanotubes (CNTs) are among the strongest and stiffest contender to be used as filler to elevate the properties of epoxy. The aim of this research work is to evaluate the structural, thermal, and morphological properties of multiwalled carbon nanotubes (MWCNTs) hybridized with silver, copper and silver/copper nanoparticles (Ag/CuNP) obtained via chemical reduction of aqueous salts assisted with sodium dodecyl sulphate (SDS) as stabilizing agent. The MWCNTs/NP was further incorporated in DGEBA (epoxy) using ethyl cellulose as hardener.

BCAP is a centriolar satellite protein and inhibitor of ciliogenesis.

The centrosome and cilium are organelles with important roles in microtubule organisation, cell division, cell signalling, embryogenesis and tissue homeostasis. The two organelles are mutually exclusive. The centriole/basal body is found at the core of the centrosome (centriole) or at the base of the cilium (basal body) and to change which organelle is present in a cell requires modification to the centriole/basal body both in terms of composition and sub-cellular localisation.

Memory Enhancing Effect of Black Pepper in the AlCl3 Induced Neurotoxicity Mouse Model is Mediated Through Its Active Component Chavicine.

Unlabelled: Black pepper (Piper nigrum Linn.) has vital pharmacological properties with profound effects on central nervous system. Neurotoxic agents like Aluminum Chloride (AlCl3) cause the oxidative stress and result in improper processing of amyloid proteins leading to accumulation of amyloid β plaques.

Microcephaly models in the developing zebrafish retinal neuroepithelium point to an underlying defect in metaphase progression.

Autosomal recessive primary microcephaly (MCPH) is a congenital disorder characterized by significantly reduced brain size and mental retardation. Nine genes are currently known to be associated with the condition, all of which encode centrosomal or spindle pole proteins. MCPH is associated with a reduction in proliferation of neural progenitors during fetal development.

The centriolar satellite proteins Cep72 and Cep290 interact and are required for recruitment of BBS proteins to the cilium.

Defects in centrosome and cilium function are associated with phenotypically related syndromes called ciliopathies. Centriolar satellites are centrosome-associated structures, defined by the protein PCM1, that are implicated in centrosomal protein trafficking. We identify Cep72 as a PCM1-interacting protein required for recruitment of the ciliopathy-associated protein Cep290 to centriolar satellites.