Analyzing Joshimath's sinking: causes, consequences, and future prospects with remote sensing techniques.

The Himalayas are highly susceptible to various natural disasters, such as the tectonically induced land deformation, earthquakes, landslides, and extreme climatic events. Recently, the Joshimath town witnessed a significantly large land subsidence activity. The phenomenon resulted in the development of large cracks in roads and in over 868 civil structures, posing a significant risk to inhabitants and infrastructure of the area.

An overview of green synthesized silver nanoparticles towards bioactive antibacterial, antimicrobial and antifungal applications.

Present review emphatically introduces the synthesis, biocompatibility, and applications of silver nanoparticles (AgNPs), including their antibacterial, antimicrobial, and antifungal properties. A comprehensive discussion of various synthesis methods for AgNPs, with a particular focus on green chemistry mediated by plant extracts has been made. Recent research has revealed that the optical properties of AgNPs, including surface plasmon resonance (SPR), depend on the particle size, as well as the synthesis methods, preparation synthesis parameters, and used reducing agents.

Study of dynamics in surface ice flow rate of glaciers in Hunza basin, Karakoram.

Glaciers in the Karakoram region are widely recognized for their historical surging phenomenon. Accurate field-based glacier monitoring is challenging in the Karakoram due to the presence of mixed-nature glaciers that are advancing, receding, and surging. Many geographers came to the opinion that surging is a thermally controlled activity in the Karakoram as opposed to a hydrologically controlled activity as a result of characteristics including high-altitude warmth, precipitation, and accumulation patterns of these glaciers.

Glacier mass balance estimation in Garhwal Himalaya using improved accumulation area ratio method.

Water requirements of the mountain communities living in the Himalaya are supported by snow and glacier melt. The availability of water from the source depends on numerous climatic and glacier parameters. One key parameter is mass balance, which helps to assess the glacier health and future water availability.

Application of "OTSU"-an image segmentation method for differentiation of snow and ice regions of glaciers and assessment of mass budget in Chandra basin, Western Himalaya using Remote Sensing and GIS techniques.

In this study, an image segmentation algorithm ("OTSU") is applied for differentiation of snow/ice regions followed by interpretation of snowlines and estimation of mass budget of glaciers in Chandra basin, Western Himalaya, India between 2014 and 2020. The observations strongly suggest that the OTSU method can be used to differentiate the snow and ice regions on a glacier accurately from any satellite image, irrespective of the sensor characteristics. Also, this method suits well to delineate the snowlines for large sample of glaciers, other than the manual interpretation and semi-automated methods.

Assessment of runoff in Chandra river basin of Western Himalaya using Remote Sensing and GIS Techniques.

The runoff of Chandra river basin in the Himalayan India was assessed using a hydrological model combined with satellite remote sensing observations. During a test period between 2000 and 2015, in situ measurements of runoff and meteorological parameters were conducted in the glacial catchment areas of Sutridhaka and Chhotashigri. A good agreement was found between the observed and predicted runoff (correlation R > 0.

Streamflow modeling and contribution of snow and glacier melt runoff in glacierized Upper Indus Basin.

The Upper Indus Basin has a large concentration of glaciers and mainly fed by snow and glacier melt. These melt runoffs are the primary driver of discharge and significantly contribute to Indus flows. Therefore, the present study was undertaken in the Upper Indus Basin (UIB) up to the Besham Quila site.

Glacial changes over the Himalayan Beas basin under global warming.

We simulated and analyzed the glacier dynamics over the Beas basin (situated in the north-western Himalayas) for the present (1980-2015) and future climates (2006-2100) under RCP4.5 and RCP8.5 global warming scenarios.

Glaciohydrology of the Himalaya-Karakoram.

Understanding the response of Himalayan-Karakoram (HK) rivers to climate change is crucial for ~1 billion people who partly depend on these water resources. Policy-makers tasked with sustainable water resources management require an assessment of the rivers' current status and potential future changes. We show that glacier and snow melt are important components of HK rivers, with greater hydrological importance for the Indus basin than for the Ganges and Brahmaputra basins.

Neuroprotective Effects of Stem Extract in Transgenic Mice Overexpressing Amyloid Precursor Protein.

To mimic Alzheimer's disease, transgenic mice overexpressing the amyloid precursor protein (APP) were used in this study. We hypothesize that the neuroprotective effects of ETAS®50, a standardized extract of stem produced by Amino Up Co., Ltd.

Author Correction: Spatial distribution of decadal ice-thickness change and glacier stored water loss in the Upper Ganga basin, India during 2000-2014.

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Spatial distribution of decadal ice-thickness change and glacier stored water loss in the Upper Ganga basin, India during 2000-2014.

Himalayan glaciers have long been the focus of glaciologists across the world while trying to understand the contrasting patterns of elevation and mass changes. However, with limited number of ground observations, a comprehensive assessment of mass balance on a regional scale still remains elusive. Using the synoptic coverage of remote sensing data, we estimate a detailed spatial variation of glacier ice thickness change in the Central Himalaya of Uttarakhand using geodetic method, on a catchment scale.

Modulation of T Regulatory and Dendritic Cell Phenotypes Following Ingestion of , AHCC and Azithromycin in Healthy Individuals.

The probiotic Bifidus BB536 (BB536), which contains , has been shown to have enhanced probiotic effects when given together with a standardized extract of cultured mycelia (AHCC, Amino Up Co. Ltd., Sapporo, Japan).

Perioperative Probiotics or Synbiotics in Adults Undergoing Elective Abdominal Surgery: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

Objective: To define the impact of perioperative treatment with probiotics or synbiotics on postoperative outcome in patients undergoing abdominal surgery.

Background: Postoperative surgical infection accounts for a third of all cases of sepsis, and is a leading cause of morbidity and mortality. Probiotics, prebiotics, and synbiotics (preparations that combine probiotics and prebiotics) are nutritional adjuncts that are emerging as novel therapeutic modalities for preventing surgical infections.

Hydrodynamic moraine-breach modeling and outburst flood routing - A hazard assessment of the South Lhonak lake, Sikkim.

The presence of glacial lakes in the Himalaya makes it a potential mountain hazard, as catastrophic failure of such waterbodies may lead to high-magnitude glacial lake outburst flood (GLOF) events that can cause significant damage to the low-lying areas. The present study evaluates the hazard potential of the South Lhonak lake located in the state of Sikkim, using both one and two-dimensional hydrodynamic modeling approaches. Different breach parameters were calculated based on the lake bathymetry and moraine dimensions.

Untangling the water-food-energy-environment nexus for global change adaptation in a complex Himalayan water resource system.

Holistic water management approaches are essential under future climate and socio-economic changes, especially while trying to achieve inter-disciplinary societal goals such as the Sustainable Development Goals (SDGs) of clean water, hunger eradication, clean energy and life on land. Assessing water resources within a water-food-energy-environment nexus approach enables the relationships between water-related sectors to be untangled while incorporating impacts of societal changes. We use a systems modelling approach to explore global change impacts on the nexus in the mid-21st century in a complex western Himalayan water resource system in India, considering a range of climate change and alternative socio-economic development scenarios.

Assessing controls on mass budget and surface velocity variations of glaciers in Western Himalaya.

This study analyses spatially resolved estimates of mass budget and surface velocity of glaciers in the Zanskar Basin of Western Himalaya in the context of varying debris cover, glacier hypsometry and orientation. The regional glacier mass budget for the period of 1999-2014 is -0.38 ± 0.

Assessment of snow-glacier melt and rainfall contribution to stream runoff in Baspa Basin, Indian Himalaya.

Hydrological regimes of most of the Himalayan river catchments are poorly studied due to sparse hydro-meteorological data. Hence, stream runoff assessment becomes difficult for various socio-industrial activities in the Himalaya. Therefore, an attempt is made in this study to assess the stream runoff of Baspa River in Himachal Pradesh, India, by evaluating the contribution from snow-ice melt and rainfall runoff.

A Rare Case of Topiramate Induced Secondary Acute Angle Closure Glaucoma.

Secondary Acute Angle Closure Glaucoma (AACG) is a known side effect of Topiramate (TPM). Here, we present a case report of a 47-year-old male who was started on TPM 25 mg/day for migraine. He presented to the ophthalmology department of our hospital with sudden blurring of vision and colored halos after one day of starting TPM.

Active hexose correlated compound modulates LPS-induced hypotension and gut injury in rats.

We hypothesized that AHCC; (Amino UP Chemical Co., Ltd., Sapporo, Japan), a mushroom mycelium extract obtained from liquid culture of Lentinula edodes, restores immune function in LPS-induced inflammation in the gut, especially when the nitric oxide signaling pathway is impaired.

Comparison of the Posterior Capsule Rupture Rates Associated with Conventional (Start to Finish) Versus Reverse Methods of Teaching Phacoemulsification.

Purpose: Comparison of the rates of posterior capsule rupture (PCR) associated with conventional versus a reverse method of teaching phacoemulsification.

Methods: Trainees were taught conventional (start-to-finish) phacoemulsification beginning with an incision (tunnel construction) to capsulorhexis, sculpting, nucleus cracking, segment removal, cortex aspiration, intraocular lens implantation, and viscoelastic removal. In the reverse method, after incision and capsulorhexis, the trainees were progressively taught viscoelastic wash, cortex aspiration, segment removal, nucleus cracking, sculpting, and intraocular lens implantation.

AHCC Activation and Selection of Human Lymphocytes via Genotypic and Phenotypic Changes to an Adherent Cell Type: A Possible Novel Mechanism of T Cell Activation.

Active Hexose Correlated Compound (AHCC) is a fermented mushroom extract and immune supplement that has been used to treat a wide range of health conditions. It helps in augmentation of the natural immune response and affects immune cell activation and outcomes. The goal of this project was to study and understand the role and mechanisms of AHCC supplementation in the prevention of immunosuppression through T cell activation.