A prospective study for prevalence and/or development of transfusion-transmitted infections in multiply transfused thalassemia major patients.

Objective: To evaluate the rate of seropositivity to hepatitis B and C and Human Immunodeficiency Virus (HIV) infections among children with β-thalassemia major receiving multiple transfusions in Ahmedabad, India, compared with healthy controls.

Materials And Methods: The study was performed during January 2007 to January 2009 on multi-transfused children suffering with β-thalassemia major registered in the Prathama Blood Centre, Ahmedabad; Jeevandeep hospital, Ahmedabad; and Red Cross Blood Centre, Ahmedabad, and investigated for the prevalence and development of transfusion-transmitted infections. Hepatitis B surface Antigen (HBsAg), anti-Hepatitis C Virus (HCV) Antibodies (Ab), and HIV Ab were checked using a fourth-generation Enzyme-Linked Immunosorbent Assay (ELISA).

Software reuse reference model approach in developing an automated medical information system (AMIS) for improving health care practice.

Objective: To evaluate patient acceptance of an automated medical information system specific to headache.

Background: Studies suggest that automated tools may help health care delivery systems to be efficient and effective, but patient satisfaction remains a major concern.

Methods: We adapted our software reuse reference model and Unified Modeling Language to apply the domain model to the headache population.