The molecular imprinting effect of propranolol and dibenzylamine as model templates: Binding strength and selectivity.

Recent studies have shown anomalies with the most studied non-covalent molecularly imprinted polymer, the propranolol imprinted one. This imprinted polymer, like many others, binds more template than the non-imprinted control polymer, but its selectivity in template adsorption is only slightly or not at all improved by imprinting, depending on the compound compared. The reasons for this anomaly are discovered here.