Changes of Subjective Symptoms and Tear Film Biomarkers following Femto-LASIK.

Femtosecond laser-assisted in situ keratomileusis (Femto-LASIK) represents a common treatment modality in refractive surgery and shows excellent results in terms of safety, efficacy, predictability, and long-term stability. However, patients may be affected by dry eye symptoms. The aim of this study was to identify a potential association between subjective dry eye symptoms, objective dry eye markers, and possible changes in the tear film, which could be a target for future therapy development.

[Long-term outcomes of PRK, LASIK and SMILE].

Background: Patients and refractive surgeons have a legitimate interest in the long-term results of the most commonly used laser procedures for correction of ametropia.

Objective: To assess the safety, predictability, stability and late complications according to the current recommendations of the committee for refractive surgery (KRC).

Methods: Literature search in PubMed with the search term "long-term outcome" combined with either "PRK", "LASIK" or "SMILE".

Detection of postlaser vision correction ectasia with a new combined biomechanical index.

Purpose: To validate and evaluate the use of a new biomechanical index known as the Corvis biomechanical index-laser vision correction (CBI-LVC) as a method for separating stable post-LVC eyes from post-LVC eyes with ectasia.

Setting: 10 clinics from 9 countries.

Design: Retrospective, multicenter, clinical study.

Epi-Bowman keratectomy versus alcohol-assisted photorefractive keratectomy: wound healing and complications.

Purpose: In Epi-Bowman Keratectomy™ (EBK), a new dynamic multi-blade single-use device (Epi-Clear™, Orca Surgical, Israel) is utilized to remove the epithelium by sweeping movements across the corneal surface. Epithelial cells are discarded. Alcohol or other chemical agents are not utilized.

Repeatability and reproducibility of manifest refraction.

Purpose: To evaluate the intraexaminer repeatability and the interobserver reproducibility of manifest refraction.

Setting: Tertiary referral center.

Design: Retrospective study.

Results of thin-cap small-incision lenticule extraction.

Purpose: To evaluate the influence of a thin cap in small-incision lenticule extraction (SMILE) for the correction of myopia or myopic astigmatism.

Setting: Tertiary care private practice.

Methods: A chart review of 102 eyes of 51 patients was performed.

Thermal Load During Corneal Excimer Laser Ablation: Impact of Different Ablation Parameters.

Purpose: To characterize the impact of different ablation parameters on the change in peak corneal temperature during corneal excimer laser ablation.

Methods: Forty-two ablations were performed (21 on polymethylmethacrylate [PMMA] and 21 on porcine eyes) simulating photorefractive keratectomy (PRK), transepithelial PRK, and laser in situ keratomileusis (LASIK) treatments. Each ablation was recorded using infrared thermography.

Clinical outcomes of small incision lenticule extraction versus advanced surface ablation in low myopia.

Purpose: To compare the visual and refractive outcomes of small incision lenticule extraction and advanced surface ablation for low myopia or myopic astigmatism.

Methods: Retrospective, observational case series of our first 50 consecutive small incision lenticule extraction patients compared to refraction-matched 50 advanced surface ablation treatments with attempted spherical equivalent correction ⩽-3.5 D, astigmatism ⩽-1.

Varifocal Versus Monofocal LASIK in Presbyopic Hyperopic Eyes.

Purpose: To compare varifocal (SupraCor; Technolas Perfect Vision GmbH, Munich, Germany) to monofocal (Zyoptix TissueSaving; Bausch & Lomb, Rochester, NY) LASIK in patients with hyperopic presbyopia.

Methods: In this prospective, non-randomized, comparative case series, consecutive patients with hyperopia, presbyopia, and emmetropia as target refraction were bilaterally treated with varifocal (8 patients) or monofocal (7 patients) LASIK. The study was designed for 35 patients, but was terminated early after interim analysis.

Small incision lenticule extraction for the correction of high myopia.

Purpose: Excimer laser-based refractive procedures can have less predictable results when used for correcting high myopia than when used for moderate myopia. Small incision lenticule extraction might overcome this weakness. However, small incision lenticule extraction is only Food and Drug Administration approved for use in myopic eyes up to -8 D with astigmatism of -3 D or less.

Flap Melting Over Corneal Inlay for Hyperopic Correction.

Purpose: To report two cases of flap melting over corneal inlays for hyperopic correction several years after implantation.

Methods: The corneal inlay (+6.00 diopters [D]; PermaVision intracorneal lens; Anamed Inc.

Small-incision lenticule extraction for the correction of myopic astigmatism.

Purpose: To report the outcomes of small-incision lenticule extraction (SMILE) in myopic eyes with astigmatism of 1.0 to 3.0 diopters (D).

Atypical endophthalmitis after intraocular collamer lens implantation.

Unilateral endophthalmitis occurred after bilateral immediately sequential intraocular collamer lens (Visian Implantable Collamer Lens) implantation for the correction of myopic astigmatism in a 49-year-old woman. The surgeries and initial recovery were unremarkable. However, after 3 days, the patient noticed increasing blurring of vision in the left eye and presented to our clinic.

Corneal Ectasia After LASIK Combined With Prophylactic Corneal Cross-linking.

Purpose: To report a case of unilateral corneal ectasia following LASIK surgery combined with prophylactic corneal cross-linking (CXL) in a young patient.

Methods: Case report.

Results: Preoperative topography was unremarkable in both eyes with a minimum corneal thickness of 554 μm in the right eye and 546 μm in the left eye.

Anterior and posterior corneal changes after crosslinking for keratoconus.

Purpose: To evaluate anterior and posterior changes in corneal topography and tomography after corneal crosslinking (CXL) in eyes with progressive keratoconus.

Methods: Scheimpflug analyses (Pentacam, Oculus) of 20 eyes with keratoconus performed before and after corneal CXL were included into retrospective analysis. Mean follow-up was 2 years.

The effect of riboflavin/UVA collagen cross-linking therapy on the structure and hydrodynamic behaviour of the ungulate and rabbit corneal stroma.

Purpose: To examine the effect of riboflavin/UVA corneal crosslinking on stromal ultrastructure and hydrodynamic behaviour.

Methods: One hundred and seventeen enucleated ungulate eyes (112 pig and 5 sheep) and 3 pairs of rabbit eyes, with corneal epithelium removed, were divided into four treatment groups: Group 1 (28 pig, 2 sheep and 3 rabbits) were untreated; Group 2 (24 pig) were exposed to UVA light (3.04 mW/cm(2)) for 30 minutes and Group 3 (29 pig) and Group 4 (31 pig, 3 sheep and 3 rabbits) had riboflavin eye drops applied to the corneal surface every 5 minutes for 35 minutes.