Publications by authors named "Anika Klingler"

Article Synopsis
  • - Bone-tendon junctions are weak points prone to injury, especially in young males, with the tibial tubercle being a key area susceptible to conditions like Osgood Schlatter disease from chronic trauma.
  • - While repetitive trauma leads to conditions like OSD in kids, adults typically face issues like distal patellar tendon ruptures around their 30s-40s.
  • - This text presents a rare case of a 15-year-old soccer player who experienced a fracture of the tibial tubercle and a simultaneous rupture of the patellar tendon, alongside a review of related medical literature.
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SPARCL1 is a matricellular protein with anti-adhesive, anti-proliferative and anti-tumorigenic functions and is frequently downregulated in tumors such as colorectal carcinoma or non-small cell lung cancer. Studies have identified SPARCL1 as an angiocrine tumor suppressor secreted by tumor vessel endothelial cells, thereby exerting inhibitory activity on angiogenesis and tumor growth, in colorectal carcinoma. It is unknown whether SPARCL1 may exert these homeostatic functions in all organs and in other species.

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