Publications by authors named "Anika Garg"

Importance: Hypertension affects 6% of all children, and its prevalence is increasing. Childhood hypertension tracks into adulthood and is associated with subclinical cardiovascular disease; however, there is a lack of evidence linking childhood hypertension to cardiovascular outcomes, which may contribute to underdiagnosis and undertreatment.

Objective: To determine the long-term associated risk of major adverse cardiac events (MACE) among children diagnosed with hypertension.

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Article Synopsis
  • * Researchers analyzed 1,767 potential studies and included 55 eligible RCTs, finding that reporting quality significantly improved after the CONSORT guidelines were published, with an average increase of 8.5 checklist items reported.
  • * The analysis highlighted that reporting quality varied significantly, suggesting that certain study characteristics influenced how well researchers adhered to the CONSORT checklist before and after the guidelines were introduced.
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The global prevalence of primary hypertension has been increasing both in children and in the adolescent and adult populations and can be attributed to changes in lifestyle factors with an obesity epidemic, increased salt consumption, and sedentary lifestyles. Childhood blood pressure is the strongest predictor of adult hypertension. Although hypertension in adults is associated strongly with an increased risk for cardiovascular disease, chronic kidney disease, and mortality, outcomes in children are defined less clearly.

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