Publications by authors named "Aniele C R Leao"
Article Synopsis
- - There is a unique fungal infection called chromoblastomycosis that can spread to the nervous system from chronic skin cases in healthy individuals, linked to a family of fungi known for their ability to break down certain chemicals.
- - Researchers conducted genomic analysis on a specific strain of this fungus, resulting in insights about its 34.8 Mb genome, which contains 12,217 genes related to its survival and pathogenic abilities.
- - The study confirmed that the fungus can infect animal models and highlighted its opportunistic nature, showing it has both ecological adaptations for thriving in harsh conditions and the ability to infect humans.
The species belonging to the genus Fonsecaea are the main causative agents of chromoblastomycosis. The invasive potential of Fonsecaea differs significantly among its various sibling species. Moreover, the lack of clarity on the virulence and availability of precise markers to distinguish and detect Fonsecaea species is attributed to the different ways of dissemination and pathogenicity.
View Article and Find Full Text PDFA draft genome sequence of type strain CBS 980.96 was obtained. This species was first isolated from a cat with cerebral phaeohyphomycosis in Queensland, Australia.
View Article and Find Full Text PDFOn the basis of multilocus phylogenetic data, Fonsecaea nubica was described in 2010 as a molecular sibling of F. monophora, an established agent of the human skin disease chomoblastomycosis in tropical zones. Genome analysis of these pathogens is mandatory to identify genes involved in the interaction with host and virulence.
View Article and Find Full Text PDFThe black yeast Fonsecaea monophora is one of the main etiologic agents of chromoblastomycosis in humans. Its pathogenicity profile is more invasive than that of related Fonsecaea species, causing brain infection in addition to (sub)cutaneous infections.
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