Effects of vancomycin linoleic acid nanoparticles on male reproductive indices of Sprague-Dawley rats.

The management of bacterial infections, especially trains of methicillin-resistant observe in health care settings, has markedly improved with the introduction of established drugs but using newer nano-based formulations. This study investigates the effects of vancomycin-linoleic acid nanoparticles on testicular tissue in an experimental animal model. Twenty-five adult male Sprague-Dawley rats maintained at the Animal House of the Biomedical Resources Unit were assigned to five groups namely E - solid lipid nanoparticles; F - vancomycin solid lipid nanoparticle; G - linoleic acid nanoparticle; H - vancomycin linoleic acid; and A - control.

Scapular length estimation from anatomical landmarks: an osteometry and radiographic evaluation using regression equations.

Estimation of body length has been achieved from the measurements of the scapular with relative accuracy by researches in recent times. This research hypothesized that the landmarks on the scapular and on the x-ray radiographs could be used to predict scapular length and elucidated the landmarks that best estimate the scapular length. A total of 600 scapulae and 600 anterior-posterior x-ray radiographs were used for the study.

Renal histopathological and biochemical changes following adjuvant intervention of and antiretroviral therapy in diabetic rats.

Objectives: Diabetic nephropathy (DN) is an important primary cause of end-stage kidney disease. This study explores the mechanisms of the reno-protective effects of () in diabetic rats following treatment with highly active antiretroviral therapy (HAART) regimen triplavar.

Materials And Methods: Adult male Sprague-Dawley rats (n=48) were divided into 7 groups (A-G).

Effect of long-term administration of Cinnamomum cassia silver nanoparticles on organs (kidneys and liver) of Sprague-Dawley rats.

This study investigated the toxic effects of silver on the kidneys and livers of Sprague-Dawley rats after administering multiple doses of silver nanoparticles synthesized using extracts of Cinnamomum cassia (CcAgNPs). Twenty-four Sprague-Dawley rats (250 ± 20 g) were randomly assigned to four groups (A-D) of six animals per group and treated for 8 weeks. Group A was administered 200 mg/kg of Cinnamon Cassia extract (Cc), group B 5 mg/kg of CcAgNPs, group C 10 mg/kg of CcAgNPs, and group D normal saline.

Histological and biochemical effects of Cinnamomum cassia nanoparticles in kidneys of diabetic Sprague-Dawley rats.

This study investigated the antidiabetic activity of Cinnamomum cassia (C. cassia, Cc) silver nanoparticles (CcAgNPS) and effects of C. cassia on the kidneys of rats with induced type 2 diabetes.

Nephrotoxicity and highly active antiretroviral therapy: Mitigating action of .

() is known for its antioxidant and antidiabetic properties. The aim of this study is to investigate the renoprotective effects of in rats following treatment with highly active antiretroviral therapy (HAART) regimen triplavar. Adult male Sprague-Dawley rats weighing 178.

Investigating Organ Toxicity Profile of Tenofovir and Tenofovir Nanoparticle on the Liver and Kidney: Experimental Animal Study.

Tenofovir nanoparticles are novel therapeutic intervention in human immunodeficiency virus (HIV) infection reaching the virus in their sanctuary sites. However, there has been no systemic toxicity testing of this formulation despite global concerns on the safety of nano drugs. Therefore, this study was designed to investigate the toxicity of Tenofovir nanoparticle (NTDF) on the liver and kidney using an animal model.