Publications by authors named "Ani A Avetisyan"
J Biomol Struct Dyn
September 2022
Article Synopsis
- The study investigates how a water-soluble porphyrin, HTOEtPyP4, and its manganese derivative, MnTOEtPyP4, bind to calf thymus DNA using various scientific techniques including UV/Vis spectrophotometry and Circular Dichroism.
- Results indicate that at low concentrations, porphyrins engage with DNA through one binding mode, while at higher concentrations, they display two distinct binding modes.
- Thermal melting analysis reveals that these porphyrins help stabilize the double-helical structure of DNA, and evidence of different melting curves suggests varying interactions based on concentration.
