Publications by authors named "Anh N Q Vo"
Article Synopsis
- Overexpression of SNAI1, a key regulator of the epithelial-to-mesenchymal transition (EMT), is shown to play a significant role in the development of human acute myeloid leukemia (AML) by affecting cell differentiation and promoting the growth of immature myeloid cells.
- Research indicates that elevated SNAI1 levels can lead to increased self-renewal and proliferation of these cells, suggesting its importance in AML pathology.
- The study highlights a previously unknown interaction between SNAI1 and the histone demethylase KDM1A/LSD1, providing new insights into leukemia mechanisms and potential treatment strategies involving LSD1 inhibitors.
