Publications by authors named "Angielys Zamora"
Introduction: While the general immune response to Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) is well-understood, the long-term effects of Human Immunodeficiency Virus-1/Severe Acute Respiratory Syndrome-Coronavirus-2 (HIV-1/SARS-CoV-2) co-infection on the immune system remain unclear. This study investigates the immune response in people with HIV-1 (PWH) co-infected with SARS-CoV-2 to understand its long-term health consequences.
Methods: A retrospective longitudinal study of PWH with suppressed viral load and SARS-CoV-2 infection was conducted.
Introduction: Urine free cortisol measurements are routinely performed to evaluate hypercortisolism. Despite their analytical inaccuracy, immunoassay-based methods are frequently used. Advances in liquid chromatography-high-resolution mass spectrometry (LC-HRMS) facilitate the incorporation of powerful diagnostic tools into clinical laboratories.
View Article and Find Full Text PDFArticle Synopsis
- Youth with vertically acquired HIV (YWVH) show immune abnormalities despite being on antiretroviral treatment (ART), especially with heightened T-cell activation and exhaustion levels.
- A study comparing YWVH to HIV-negative youth found strong correlations between immune activation markers and the CD4/CD8 ratio, suggesting this ratio may help in tracking disease progression.
- Overall, ART appears to only partially restore normal immune function in YWVH, emphasizing the need for ongoing monitoring and adaptation of treatment strategies.