Assessment of 2'-Fucosyllactose and Lacto-N-Neotetraose Solution as an Irrigant in -Infected Root Canals: An In Vitro Study.

Background: Given the lack of an ideal endodontic irrigant on the market, this study evaluates the antimicrobial potential of a formulated solution of 2'-fucosyllactose and lacto-N-neotetraose against within infected root canals, and explores any associated impacts related to the duration of irrigation.

Methods: 32 single-rooted teeth extracted for periodontal reasons were infected with , and subsequently subjected to endodontic treatment with two different irrigation systems: sodium hypochlorite or a solution of 2'-fucosyllactose and lacto-N-neotetraose. These samples were then incubated in sterile culture media at 37 °C to observe microbial activity through turbidity.