Publications by authors named "Angelita C Melo"

Article Synopsis
  • The review focused on identifying phenolic compounds in pitayas (dragon fruit) through literature published from 2013 to 2023.
  • After analyzing 601 studies, 57 were selected, revealing that these compounds have health benefits such as antioxidant and anti-inflammatory properties, as well as potential treatments for cancer, diabetes, and obesity.
  • Key findings included the prevalence of flavonoids like kaempferol and rutin, plus various acids and betalains, hinting at their use as natural colorants in the food industry and suggesting the need for more research on their nutritional benefits.
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The baru ( Vog.), a fruit native to the Cerrado biome, is well-known for its almonds, which are extensively exploited and exported. Unfortunately, the remaining parts of this fruit are often discarded.

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Objective: To assess the clinical communication characteristics of pharmacy undergraduates, estimate differences in this specific competency, and produce recommendations for further education and training.

Methods: Analysis of communication competence between 110 pharmacy students in the last graduation year from each of the 5 Brazilian regions and a simulated patient with complaints of mild allergic rhinitis passive of resolution with non-prescription medicines. The simulated appointment was recorded, and the video was analyzed using the 2 main elements: biomedical/task-focused and socio-emotional exchange of the Roter Interaction Analysis System.

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Article Synopsis
  • Grumixama is a native Brazilian fruit with potential food benefits, rich in polyphenols and volatile compounds that enhance its flavor and aroma.
  • The study aimed to evaluate the effectiveness of different solid-phase microextraction (SPME) fibers in extracting volatile organic compounds from grumixama pulp and to optimize extraction conditions such as time, temperature, and sample weight.
  • The results showed that the DVB/CAR/PDMS fiber was most efficient, identifying the highest number of volatile compounds, primarily sesquiterpenes, under optimal conditions of 75 °C, 2.0 g sample weight, and 20 minutes of adsorption time.
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, also known as rumberry, is a tree native to the Brazilian Atlantic Forest, where its fruits have the potential for commercial use. This study evaluates the antioxidant potential, determines the phytochemical profile, and chemically characterizes the rumberry fruit. Accessions were sampled from the Rumberry Active Germplasm Bank of the Federal University of Alagoas, Brazil.

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The Brazilian National Health System (BR-NHS) is one of the largest public health systems in the world. In 2019 Brazil had 114,352 community pharmacies (76.8% private owned), that represent the first point of access to healthcare in Brazil due to their wide distribution.

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Objective: To identify the determinants of tuberculosis-related variables in the various regions of Brazil and evaluate trends in those variables over the ten-year period preceding the end of the timeframe defined for the United Nations Millennium Development Goals (MDGs).

Methods: This was an ecological analytical study in which we utilized eight national public databases to investigate the 716,971 new tuberculosis cases reported between 2006 and 2015.

Results: Over the study period, there were slight reductions in the prevalence, incidence, and mortality associated with tuberculosis.

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Objective: To evaluate the training and standardization methods of multiple simulated patients (SPs) performing a single scenario in a multicenter study.

Methods: A prospective quasi-experimental study, using a multicenter approach, evaluated the performance of five different individuals with the same biotype during a simulation session in a high-fidelity environment. The SPs training and standardization process consisted of four steps and six web or face-to-face mediated: Step 1: simulation scenario design and pilot test.

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Objective: To analyze the context of drug use in children aged zero to five years old.

Methods: Cross-sectional study based on interviews conducted at home with caregivers (parents, uncles or grandparents) of the children enrolled in ten Family Health Strategy units across different geographical points of the city of Tubarão, Santa Catarina, Brazil.

Results: A total of 350 caregivers were interviewed, whose children's mean age was 2.

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Although uric acid is not part of any definition of metabolic syndrome, a number of studies have shown strong associations between the concentration of uric acid and metabolic syndrome or its components. The purpose of this systematic review with meta-analysis was to evaluate, using prospective interventional studies, the effects of allopurinol therapy and uric acid normalization on serum concentrations of triacylglycerol, total-cholesterol, LDL-cholesterol and HDL-cholesterol in hyperuricemic subjects. A systematic search of the PubMed and Scopus databases was performed following the guidelines described in the PRISMA statement.

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Background: The complexity of a medication regimen is related to the multiple characteristics of the prescribed regimen and can negatively influence the health outcomes of patients.

Objective: To propose cut-off points in the complexity of pharmacotherapy to distinguish between patients with low and high complexities seen in a primary health care (PHC) setting to enable prioritization of patient management.

Methods: This is a cross-sectional study, which included 517 adult and elderly patients, analyzing different cut-off points to define the strata of low and high pharmacotherapy complexities based on percentiles of the population evaluated.

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This was descriptive study carried out in a medium-sized Brazilian city. In ≤ 15-year-old contacts of index cases of active pulmonary tuberculosis, we assessed compliance with the Brazilian national guidelines for tuberculosis control. We interviewed 43 contacts and their legal guardians.

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Article Synopsis
  • The study analyzed healthcare usage between injection drug users (IDUs) and non-IDUs at HIV/AIDS treatment centers from 1986 to 2002, focusing on demographics and treatment received.
  • Among 170 patients, 39.4% were IDUs, primarily male with low education levels, and many did not receive necessary ARV prescriptions or lab requests at their first consultation.
  • Unlike non-IDUs, who showed increased healthcare utilization following Brazil's universal health policy, IDUs experienced worse outcomes and challenges in adhering to ARV therapy, indicating significant disparities in treatment access.
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