Multiplicity of Carbapenemase-Producers Three Years after a KPC-3-Producing ST147-K64 Hospital Outbreak.

Carbapenem resistance rates increased exponentially between 2014 and 2017 in Portugal (~80%), especially in . We characterized the population of carbapanemase-producing Enterobacterales (CPE) infecting or colonizing hospitalized patients (2017-2018) in a central hospital from northern Portugal, where KPC-3-producing capsular type K64 has caused an initial outbreak. We gathered phenotypic (susceptibility data), molecular (population structure, carbapenemase, capsular type) and biochemical (FT-IR) data, together with patients' clinical and epidemiological information.