Publications by authors named "Angeliki Victoria Roussaki-Schulze"
The Koebner phenomenon (KP), also known as the isomorphic response, describes the process by which new lesions that are clinically and histologically identical to a patient's existing skin disease develop following trauma. Many skin diseases exhibit this characteristic, with variations that include possible, questionable, and pseudo-Koebner reactions, with the latter category occurring due to infectious agents seeding at a trauma site. Laser application, a type of controlled skin injury used for improving cutaneous lesions and skin rejuvenation, is also considered a form of trauma.
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- - This survey is the first attempt to evaluate the clarity of dermoscopic language using an AI chatbot, highlighting the interaction between dermatologists and AI in understanding complex dermoscopic terms.
- - Thirty dermatologists reviewed hypothetical skin lesion descriptions generated by the chatbot, focusing on various skin cancers and inflammatory conditions, and assessed the chatbot’s ability to suggest differential diagnoses.
- - Results showed that while the chatbot generated extensive differential diagnoses, it performed better on basal cell carcinoma (BCC) cases compared to squamous cell carcinoma (SCC) and inflammatory conditions, indicating dermatologists are more familiar with BCC dermoscopic signs.
Article Synopsis
- - Keratoacanthoma (KA) is a rapidly growing skin tumor that can appear as single or multiple lesions, particularly in certain rare genetic syndromes like Ferguson-Smith syndrome and others.
- - Treatment of these syndromes is complex because of the presence of numerous lesions and other skin cancers, exemplified by a case involving a 40-year-old woman with multiple treatment-resistant keratoacanthomas and invasive squamous cell carcinoma.
- - The woman was successfully treated with a combination of oral acitretin and topical Fluorouracil for her keratoacanthomas, while surgical intervention was used for her ulcerated cancer, and the study included a review of literature on diagnosis and treatment of similar syndromes
Biologics approved for psoriasis exhibit favorable safety profiles, and serious adverse events have rarely been reported. In this report, we present the case of a patient treated with ixekizumab, an anti-interleukin (IL)-17 agent, who 8 months later developed multiple sclerosis (MS). We also review the available literature regarding the use of anti-IL-17 agents in the context of psoriasis and pre-existing or new-onset demyelination.
View Article and Find Full Text PDFIntroduction: Many patients with chronic inflammatory dermatosis such as psoriasis usually ask about the safety of COVID-19 vaccination and if it would affect the course of their disease. Indeed, many case reports, case series and clinical studies, reporting psoriasis exacerbation following vaccination against COVID-19, were published during the pandemic. Also, many questions arise regarding the existence of exacerbating factors of these flare ups, including environmental triggers such as the insufficiency of vitamin D levels.
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