Publications by authors named "Angelika Lang"
Article Synopsis
- - The study investigates the potential of pre-treatment blood count biomarkers to predict how well patients with chronic rhinosinusitis with nasal polyps (CRSwNP) will respond to dupilumab treatment.
- - Conducted at the Medical University of Graz, it analyzed 80 patients, finding that 72.5% responded positively to dupilumab, with higher eosinophil counts linked to better treatment outcomes.
- - While eosinophil count showed potential as a predictive marker, other inflammatory measures like NLR and PLR did not demonstrate significant associations with treatment effectiveness, indicating a need for more research.
Article Synopsis
- The study evaluated the effectiveness and safety of switching between monoclonal antibodies for patients with uncontrolled chronic rhinosinusitis with nasal polyps (CRSwNP).
- Of 91 patients, only 4 (4.4%) needed to switch biologic treatments, primarily due to inadequate symptom relief or side effects.
- All patients who switched experienced significant improvement without any reported side effects, suggesting that switching biologic agents could be beneficial, though further research is needed.
This case report details the unusual occurrence of a live ant invading the middle ear cavity through a pre-existing perforation in the tympanic membrane of a 42-year-old female patient. She presented to an outpatient clinic with symptoms of sudden-onset tinnitus ("ringing") and a foreign body sensation in her left ear. Otomicroscopy revealed an oval-shaped perforation in the posterior part of the left tympanic membrane, through which a dark, moving foreign object was observed in the middle ear.
View Article and Find Full Text PDFChronic rhinosinusitis with nasal polyps (CRSwNP) significantly impacts quality of life and often presents therapeutic challenges, with biologics like dupilumab showing promise in managing severe, uncontrolled cases. The aim of this study was to assess the influence of overweight on the effectiveness of dupilumab in patients with uncontrolled CRSwNP. This retrospective study analyzed treatment outcomes of 75 CRSwNP patients receiving dupilumab, categorizing them into underweight/normal-weight (BMI ≤ 24.
View Article and Find Full Text PDFIncreasing evidence suggests a possible interaction between vitamin D and insulin-like growth factor-1 (IGF-1). We aimed to investigate effects of vitamin D supplementation on IGF-1 (primary outcome) and calcitriol (1,25(OH)₂D) concentrations (secondary outcome). This is a post-hoc analysis of the Styrian Vitamin D Hypertension Trial-a single-center, double-blind, randomized, placebo-controlled trial (RCT) conducted from 2011 to 2014 at the Medical University of Graz, Austria.
View Article and Find Full Text PDFBone turnover markers (BTMs) are used to evaluate bone health together with bone mineral density and fracture assessment. Vitamin D supplementation is widely used to prevent and treat musculoskeletal diseases but existing data on vitamin D effects on markers of bone resorption and formation are inconsistent. We therefore examined the effects of vitamin D supplementation on bone-specific alkaline phosphatase (bALP), osteocalcin (OC), C-terminal telopeptide (CTX), and procollagen type 1 N-terminal propeptide (P1NP).
View Article and Find Full Text PDFPemphigus vulgaris (PV) is a severe autoimmune bullous skin disease and is primarily associated with IgG against desmoglein 3 (dsg3), a desmosomal adhesion protein. In light of the recent association of autoreactive T helper (Th) 2 cells with active PV, the present study sought to relate the occurrence of Th2-regulated dsg3-specific autoantibody subtypes, i.e.
View Article and Find Full Text PDF["Welcome Augsburg children": home visits for young families by pediatric nurses].
Kinderkrankenschwester
November 2008