[Not Available].

In the period between March 2021 and December 2023, our Casa della Salute in Borgaretto (Torino) organized a clinic dedicated to vaccination against Covid-19 in its local and with its staff (medical, nursing and administrative). To try to inform the majority of the population about this activity, we used the social networks of the Casa della Salute (Facebook and website), the social networks of the Municipality of Beinasco and some of the local newspapers. The list of eligible subjects was shared with the ASL TO 3 and the invitation to vaccination was made via SMS from a dedicated platform, indicating the day and time of the appointment.

[Not Available].

Netaudit is a unique, voluntary network of general practitioners in Italy dedicated to conducting audits and research on their clinical practice. Unlike traditional academic research, Netaudit is driven by the grassroots efforts of primary care physicians. The project aims to provide practical tools and support for GPs seeking to improve their clinical practice through data-driven insights.

DNA repair gene expression level in peripheral blood and tumour tissue from non-small cell lung cancer and head and neck squamous cell cancer patients.

Background: The nucleotide excision repair pathway is crucial for cellular DNA integrity and the ERCC1 helicase is also potentially involved in resistance to platinum-based chemotherapy, and high levels of ERCC1 mRNA in tumours have been associated with cisplatin resistance in different human cancers. The aim of this work was to investigate the correlation between DNA repair gene expression levels in tumour tissue, normal tissue and peripheral blood samples from patients with two common human cancers, non-small cell lung cancer (NSCLC) and squamous cell carcinoma of the head and neck (HNSCC), to test if blood gene expression could be a proxy for tumour tissue gene expression to predict response to platinum-based chemotherapy.

Methods: Using RT-qPCR we determined ERCC1, ERCC2, ERCC4, XPA, XPC, XRCC1, XRCC3, APEX, OGG1, MGMT mRNA levels in fresh NSCLC, normal lung and HNSCC tissue, as well as blood, from NSCLC and HNSCC patients who were treated surgically.

Fractionated dose of cisplatin (CDDP) and vinorelbine (VNB) chemotherapy for elderly patients with advanced non-small cell lung cancer: phase II trial.

Background: The incidence of non-small cell lung cancer (NSCLC) is increasing among the elderly representing about 30% of NSCLC patients over 70 years old. The aim of this study was to evaluate the response, survival and tolerability of a modified schedule with cisplatin-vinorelbine in elderly patients with advanced NSCLC.

Methods: Between November 2001 and March 2003, 30 patients were included into the study.