Publications by authors named "Angelica P S de Albuquerque"
Biomed Pharmacother
March 2018
Article Synopsis
- The study reports the development and testing of four derivatives of 3-hydroxy-piperidine-N-benzyl-aryl-acylhydrazone for their pain-relief potential.
- Compounds 6a and 6d demonstrated significant pain relief in the tail flick test and increased pain threshold in a neuropathic pain model.
- The pain relief effects of these compounds were reversible with naloxone, indicating they work through an opioid mechanism without causing sedation or impairing motor skills.
