Correlation between corneal and contact lens deformation with changes in intraocular pressure for wearable monitoring systems.

Objective: The aim of this work is to evaluate the extent to which the eye's curvature deformation, due to changes in the intraocular pressure (IOP), can be directly tracked by an overlying contact lens.

Method: In this experimental study, using 12 cadaveric eyes, the IOP was increased from 10 to 36 mmHg, while video imaging was used to capture the three experimental variations. The deformation of the bare eye was used as a control, while the deformation of an overlying silicone grided contact lens and an overlying microfluidic IOP-sensing contact lens were examined and compared.

Effect of variations of corneal physiology on novel non-invasive intraocular pressure monitoring soft contact lens.

Glaucoma is the leading cause of irreversible blindness around the world. With its slow asymptomatic progression, there is an emphasis on early detection and frequent monitoring. A novel microfluidic contact lens has been established as a potential way to track the fluctuations of the intraocular pressure (IOP) which is a key indicator for diagnosing and monitoring glaucoma progression.

Non-invasive Intraocular pressure monitoring with contact lens.

Background: Glaucoma is the second leading cause of blindness in the world and the first leading cause of irreversible vision loss. Currently, the primary methodology of testing for the intraocular pressure (IOP) is during clinical office hours, which only provide a limited amount of information on the trends and fluctuations of the IOP. Therefore, a continuous monitoring system is required to properly determine the peaks of pressure and to negate any false results obtained by sparse, clinic hour testing.