Publications by authors named "Angelica Anichini"
Isolated chronic granulomatous meningitis remains a diagnostic challenge for the physician. Symptoms are often nonspecific and ancillary tests have low-sensitivity rates, which may delay targeted treatment and lead to increased morbidity and mortality. Here, we discuss the challenges in diagnosing and treating patients with chronic meningitis by reporting two cases of previously healthy patients who presented with granulomatous meningitis on brain biopsy.
View Article and Find Full Text PDFObjective: Coronavirus disease (COVID-19) has been associated with a large variety of neurologic disorders. However, the mechanisms underlying these neurologic complications remain elusive. In this study, we aimed at determining whether neurologic symptoms were caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) direct infection or by either systemic or local proinflammatory mediators.
View Article and Find Full Text PDFArticle Synopsis
- In 2020, significant advancements were made in blood biomarkers for Alzheimer's disease, improving diagnosis and management.
- New research focused on the treatment of status epilepticus and epilepsy, especially in women of childbearing age, alongside updated Swiss guidelines for acute stroke management and prevention.
- Progress was noted in managing NeuroMyelitis Optica Spectrum Disorder (NMO-SD), neurological presentations related to COVID-19, new treatments for migraines, and pharmacological therapies for Parkinson's disease.
Objectives: The adult or 'muscular' form of carnitine-palmitoyl-transferase II (CPT II) deficiency presents with recurrent rhabdomyolytic episodes and myoglobinuria, usually triggered by prolonged exercise. The aim of this study was to investigate a large series of patients in order to provide genotype-phenotype correlations.
Methods: Our muscle tissue bank was surveyed for patients showing attacks of rhabdomyolysis with myoglobinuria.