Publications by authors named "Angelamellisy Ndibalema"
Background: The factors that predispose to pulmonary tuberculosis (PTB) are not fully understood, However. Gene polymorphisms have been associated with PTB development.
Objectives: In this study, we investigated the relationship between LIPA gene polymorphisms and a predisposition to pulmonary tuberculosis caused by Mycobacterium tuberculosis.
Article Synopsis
- Empagliflozin (emp) shows renal protective effects against hyperglycemia-induced injury in human kidney cells, though its mechanism remains unclear.
- High glucose levels increase harmful proteins and signals related to fibrosis, while emp decreases these effects and increases HIF-1α expression, suggesting a potential protective pathway.
- Overall, emp treatment provides a protective role for renal tubular cells under high glucose conditions by reducing injury and influencing important cellular markers.