Dosage-dependent reduction of macular pigment optical density in female breast cancer patients receiving tamoxifen adjuvant therapy.

It is now increasingly common for breast cancer patients to receive adjuvant tamoxifen therapy for a period of up to 10 years. As survival rate increases, managing tamoxifen ocular toxicities is important for patients' quality of life. Macular pigments in photoreceptor cells protect against free radical damage, which can cause macular degeneration.

Plasma, aqueous and vitreous homocysteine levels in proliferative diabetic retinopathy.

Background/aims: To compare homocysteine (Hcy) concentration in the blood plasma, vitreous and aqueous of eyes with proliferative diabetic retinopathy (PDR) against control, and to investigate associations between Hcy concentration in blood plasma with that of aqueous and vitreous in these two groups.

Methods: Blood plasma, aqueous and vitreous samples were collected during combined cataract and pars plana vitrectomy from 20 eyes with PDR and 21 eyes of patients without diabetes mellitus. Hcy concentration in the samples was determined by chemiluminescent microparticle immunoassay.

Ocular trauma injuries: a 1-year surveillance study in the University of Malaya Medical Centre, Malaysia. 2008.

Purpose: To describe the epidemiology of ocular injuries presenting to the University Malaya Medical Centre (UMMC), Kuala Lumpur, Malaysia.

Design: Prospective analysis of all ocular trauma injuries presenting to the Department of Ophthalmology in UMMC from 1 January 2008 to 31 December 2008.

Participants: A total of 603 eyes of 546 patients were recruited for the study.