Publications by authors named "Angela Valero-Almazan"
Int J Mol Sci
January 2023
Article Synopsis
- Acute kidney injury (AKI) increases the chances of serious heart events and mortality, but the reasons behind this link are still unclear.
- Research shows that a decrease in the anti-aging factor klotho may worsen heart damage following AKI, as seen in experiments with mice that had reduced klotho levels.
- Specifically, the study found that mice with lower klotho expression experienced impaired heart cell function and more disturbances in calcium handling after AKI, suggesting that targeting klotho expression could be a new treatment strategy for protecting heart health in AKI patients.
