Publications by authors named "Angela Travaglione"
Article Synopsis
- Scientists are trying to make embryo culture better in labs for helping with pregnancies because current methods lag behind the ways we select embryos.
- Research shows that embryos grown in labs (IVP) don’t do as well as those developed naturally (IVD), especially in animals like cows, which leads to fewer pregnancies and live births.
- Improving embryo culture conditions, by understanding how embryos grow and interact with their environment, could help boost success rates in assisted reproductive technology.
Article Synopsis
- The demand for rare earth elements, particularly gadolinium (Gd), is rising in various industries, but its environmental impact is becoming a concern, especially in marine ecosystems due to wastewater release.
- This study investigates the ecotoxicological effects of Gd, specifically its detrimental effects on embryonic development and sperm functionality in marine organisms.
- Findings reveal Gd's significant embryotoxic effects at high concentrations and a notable decrease in sperm motility, indicating serious ecological risks associated with its presence in the environment.
The possibility of detecting the developmental competence of individually cultured embryos through analysis of spent media is a major current trend in an ART setting. However, individual embryo culture is detrimental compared with high-density group culture due to the reduced concentration of putative embryotropins. The main aim of this study was to identify an individual culture system that is not detrimental over high-density group culture in the bovine model.
View Article and Find Full Text PDFEnhanced solute transport and steady mechanical stimulation in a novel dynamic perifusion bioreactor increase the efficiency of the culture of ovarian cortical tissue strips.
Front Bioeng Biotechnol
February 2024
We report the development and preliminary evaluation of a novel dynamic bioreactor to culture ovarian cortical tissue strips that leverages tissue response to enhanced oxygen transport and adequate mechanical stimulation. multistep ovarian tissue static culture followed by mature oocyte generation, fertilization, and embryo transfer promises to use the reserve of dormant follicles. Unfortunately, static culture of ovarian tissue does not promote development of primordial to secondary follicles or sustain follicle viability and thereby limits the number of obtainable mature oocytes.
View Article and Find Full Text PDFOvarian tissue cryopreservation prior to gonadotoxic treatment is the only recommended option for fertility preservation in prepubertal girls. Due to the technical complexity of this technique, limited number of centres across the world are equipped to offer the facility. Hence, the retrieved ovarian tissue needs to be maintained at hypothermic temperature (4 °C) for long time during shipment.
View Article and Find Full Text PDFArticle Synopsis
- Scientists are looking for better ways to grow eggs from ovarian tissue in the lab.
- They tried using a new method called a "perifusion bioreactor," which moves fluids, instead of just keeping the tissue still.
- This new method helped improve the health and quality of the follicles (the tiny sacs that hold the eggs) in both cows and humans!