Long-term visual outcomes following abusive head trauma with retinal hemorrhage.

Purpose: To report the rates of vision loss and select ocular findings after abusive head trauma (AHT) with retinal hemorrhages at a single center.

Methods: The study cohort was identified by review of billing records for patients presenting simultaneously with retinal hemorrhages and abusive head trauma at the Children's Hospital of Colorado from October 2005 to April 2017. The following data were analyzed: retinal examination at initial admission and visual acuity, other pertinent eye findings, and eye management at follow-up visits.

Glial Cell Calcium Signaling Mediates Capillary Regulation of Blood Flow in the Retina.

Unlabelled: The brain is critically dependent on the regulation of blood flow to nourish active neurons. One widely held hypothesis of blood flow regulation holds that active neurons stimulate Ca(2+) increases in glial cells, triggering glial release of vasodilating agents. This hypothesis has been challenged, as arteriole dilation can occur in the absence of glial Ca(2+) signaling.

Ischemia-induced spreading depolarization in the retina.

Cortical spreading depolarization is a metabolically costly phenomenon that affects the brain in both health and disease. Following severe stroke, subarachnoid hemorrhage, or traumatic brain injury, cortical spreading depolarization exacerbates tissue damage and enlarges infarct volumes. It is not known, however, whether spreading depolarization also occurs in the retina in vivo.