Severe burn injuries induced by PUVA chemotherapy.

Psoralen-ultraviolet A (PUVA) chemotherapy is an established treatment for certain skin diseases. Burn injury is a serious complication of PUVA therapy. Reports regarding this complication are limited.

Establishing efficient xenograft models with intrinsic vascularisation for growing primary human low-grade sarcomas.

Background: There are no xenograft models of low-grade soft tissue sarcoma. Transplant survival remains an obstacle in sarcoma xenograft models and is attributed to post-transplantation hypoxia. Models with an intrinsic tissue - engineered vascular supply may overcome this obstacle.

Surface modification by glow discharge gasplasma treatment improves vascularization of allogenic bone implants.

Sufficient induction of blood vessel ingrowth decisively influence transplant functionality. In this study, microvascular response to transplants of surface modified bone substitutes were assessed in vivo. The surface modification of allogenic bone substitutes (dehydrated human femoral head) was achieved in a double-conductive low-pressure gasplasma reactor (Ar(2) /O(2) , 13.

Enhanced neovascularization of dermis substitutes via low-pressure plasma-mediated surface activation.

Purpose: The effect of cold low-pressure plasma treatment on neovascularization of a dermis substitute was evaluated in a mouse model.

Material And Methods: Collagen-elastin matrices (Matriderm(®)) were used as scaffolds. Low-pressure argon/hydrogene plasma-treated scaffolds were transplanted into the dorsal skinfold chambers of balb/c mice (group 1, n=10).