Publications by authors named "Angela Reed"
Aim: To explore the use and impact of standardized terminologies (STs) within nursing and midwifery practice.
Introduction: The standardization of clinical documentation creates a potential to optimize patient care and safety. Nurses and midwives, who represent the largest proportion of the healthcare workforce worldwide, have been using nursing-specific and multidisciplinary STs within electronic health records (EHRs) for decades.
Background: Birmingham Women's and Children's NHS Foundation Trust was formed in February 2017 following an acquisition. The Library and Knowledge Services (LKS) merged while operating across two hospital sites. A priority for the merged Library and Knowledge Service was to integrate e-collections.
View Article and Find Full Text PDFBackground: Carcinoma in situ (CIS) is a poor prognostic finding in urothelial carcinoma. However, its significance in muscle-invasive urothelial carcinoma (MIUC) treated with neoadjuvant chemotherapy (NAC) is uncertain. We assessed the effect of CIS found in pretreatment transurethral resection of bladder tumor (TURBT) biopsies on the pathologic and clinical outcomes.
View Article and Find Full Text PDFArticle Synopsis
- The study evaluated the effectiveness and safety of dovitinib in patients with treatment-resistant non-muscle-invasive urothelial carcinoma of the bladder, specifically focusing on those with specific FGFR3 marker profiles.
- A phase II trial involved 13 patients who took dovitinib, but results showed a low six-month complete response rate of only 8%, and significant side effects were common among participants.
- The findings indicated that while dovitinib achieved drug concentrations that inhibited pFGFR3 in bladder tissue, its overall clinical efficacy was limited, suggesting that selecting patients based solely on pFGFR3 markers may not lead to better outcomes with this treatment.
Background: Study of genomic data obtained from patient biospecimens is frequent in research of subjects with prostate and other epithelial malignancies. Understanding of the characteristics of healthy men who participate in genomic research is limited.
Methods: Patients were identified through the Prostate Cancer Genetic Risk Evaluation of SNPs Study and the Indiana University Cancer Biomarker Study, 2 population-based biomarker and cohort studies.