Publications by authors named "Angela Rabe"

Norovirus is a leading cause of acute gastroenteritis and imposes a substantial disease burden. In California, USA, norovirus surveillance is limited. We evaluated correlations between wastewater norovirus concentrations and available public health surveillance data.

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Article Synopsis
  • * From May 12 to July 13, 2024, 38 states participated in testing, with 11 sites showing high levels of influenza A virus and 24 sites detecting the H5 subtype.
  • * Investigations revealed that many high-level detections corresponded with human influenza activity and identified possible animal sources, providing valuable data for future respiratory illness monitoring.
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Monitoring for COVID-19 through wastewater has been used for adjunctive public health surveillance, with SARS-CoV-2 viral concentrations in wastewater correlating with incident cases in the same sewershed. However, the generalizability of these findings across sewersheds, laboratory methods, and time periods with changing variants and underlying population immunity has not been well described. The California Department of Public Health partnered with six wastewater treatment plants starting in January 2021 to monitor wastewater for SARS-CoV-2, with analyses performed at four laboratories.

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Monitoring severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) is critical for public health management of coronavirus disease. Sequencing is resource-intensive and incompletely representative, and not all isolates can be sequenced. Because wastewater SARS-CoV-2 RNA concentrations correlate with coronavirus disease incidence in sewersheds, tracking VOCs through wastewater is appealing.

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Background: Reports on unexpected events (UEs) during blood donation (BD) inadequately consider the role of technical UEs.

Methods: Defined local and systemic UEs were graded by severity; technical UEs were not graded. On January 1, 2008, E.

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Background: Reports on unexpected donor events (UEs) during preparatory plasmapheresis (PPP) are scarce, and rarely consider technical UEs.

Methods: Defined local and systemic UEs were graded by severity; technical UEs were not graded. On January 1, 2008, E.

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