Association of the histamine N-methyltransferase C314T (Thr105Ile) polymorphism with atopic dermatitis in Caucasian children.

Study Objective: To investigate potential associations between the histamine N-methyltransferase (HNMT) gene, HNMT, C314T (Thr105Ile) polymorphism and atopic dermatitis in a cohort of Caucasian children.

Design: Prospective, multicenter, genotype-association study.

Setting: Four academic, tertiary care medical centers within the Pediatric Pharmacology Research Unit network.