Publications by authors named "Angela Peiter"
Article Synopsis
- The study investigates how aldosterone, a hormone, affects the expression of various genes in human renal epithelial cells and suggests that there may be mechanisms beyond the usual receptor pathways involved in kidney and heart disease.
- Researchers found that specific genes were significantly up-regulated after aldosterone treatment, indicating its impact on cellular processes, but some genes showed resistance to common receptor inhibitors.
- The research highlights the need for further exploration of these non-classical regulatory mechanisms to better understand why aldosterone antagonists like spironolactone may not always be effective in treating kidney disease.
