Publications by authors named "Angela N Koeberlein"
Article Synopsis
- Actin cytoskeleton assembly is crucial for cell movement and muscle contraction, with formins being key proteins that help in the creation and maintenance of actin filaments.
- The FHOD-family of formins, particularly FHOD3L, is essential for developing sarcomeres in heart cells (cardiomyocytes), yet its precise functions are not fully understood.
- Research shows that FHOD3L is involved in nucleating and briefly elongating actin filaments, and its elongation activity is vital for proper sarcomere structure and function, which has implications for understanding heart muscle diseases.
The Cdc14 phosphatase family is highly conserved in fungi. In Cdc14 is essential for down-regulation of cyclin-dependent kinase activity at mitotic exit. However, this essential function is not broadly conserved and requires only a small fraction of normal Cdc14 activity.
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