Publications by authors named "Angela Michela Immacolata Montone"

The epidemiology of Salmonella Infantis is complex in terms of its distribution and transmission. The continuous collection and analysis of updated data on the prevalence and antimicrobic resistance are essential. The present work aimed to investigate the antimicrobial resistance and the correlation among Infantis isolates from different sources through the multiple-locus variable-number of tandem repeat (VNTR) analysis (MLVA).

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Helicobacter pylori (H. pylori) is a common human pathogen causing inflammation. Recent studies have suggested a sophisticated interplay between mitochondria, innate immunity and inflammatory response, thus proposing mitochondrial disfunction as the hallmark of severe inflammatory disorders.

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In this work, the effect of an alginate-based coating loaded with hydroxyapatite/lactoferrin/quercetin (HA/LACTO-QUE) complexes during the storage of pork meat was evaluated. FT-IR spectra of HA/LACTO-QUE complexes confirmed the adsorption of QUE and LACTO into HA crystals showing the characteristic peaks of both active compounds. The kinetic releases of QUE and LACTO from coatings in an aqueous medium pointed out a faster release of LACTO than QUE.

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Article Synopsis
  • The study focuses on assessing the prevalence of foodborne illness agents, specifically a genus with two species and six subspecies, in food and animal carcasses in southern Italy from 2011 to 2021.
  • A total of 12,246 food samples and 982 animal carcass samples were analyzed, revealing an overall positive sample rate of 5.84%, with a notable increase in prevalence during the later years of the study period.
  • The most affected categories include "Meat and Meat Products," and the most frequently identified serovar was Infantis, indicating urgent need for improved control measures despite existing national and European strategies.
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Short peptides have been spiking interest owing to their significant contribution to the taste and functional properties of dry-cured ham. In this study, a suspect screening approach based on high-resolution mass spectrometry was employed for the comprehensive characterization of the short endogenous peptidome in dry-cured ham samples at different processing stages (14, 22, and 34 months). After careful manual spectra interpretation, a chemometric approach based on principal component analysis was employed for highlighting the differences between the three sets of samples.

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Non-typhoid Salmonella (NTS) represents one of the major causes of foodborne diseases, which are made worse by the increasing emergence of antibiotic resistance. Thus, NTS are a significant and common public health concern. The purpose of this study is to investigate whether selection for phage-resistance alters bacterial phenotype, making this approach suitable for candidate vaccine preparation.

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The identification of novel strategies to control ()-associated chronic inflammation is, at present, a considerable challenge. Here, we attempt to combat this issue by modulating the innate immune response, targeting formyl peptide receptors (FPRs), G-protein coupled receptors that play key roles in both the regulation and the resolution of the innate inflammatory response. Specifically, we investigated, in vitro, whether Caulerpin-a bis-indole alkaloid isolated from algae of the genus -could act as a molecular antagonist scaffold of FPRs.

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is an opportunistic, psychotropic pathogen that can live in different environments, such as plant, soil, or water surfaces, and it is associated with food spoilage. Bioactive compounds can be used as antimicrobials and can be added into packaging systems. Quercetin and lactoferrin are the best candidates for the development of a complex of the two molecules absorbed on bio combability structure as hydroxyapatite.

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Soybeans () are an excellent source of dietary proteins and peptides with potential biological activities, such as antihypertensive, anti-cholesterol, and antioxidant activity; moreover, they could prevent cancer. Also, soy contains all the essential amino acids for nutrition; therefore, it represents an alternative to animal proteins. The goal of this paper was the comprehensive characterization of medium-sized and short peptides (two to four amino acids) obtained from simulated gastrointestinal digestion.

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is a spoilage bacterium and is recognized as an agent of food poisoning. Two food-borne illnesses are caused by : a diarrheal disease, associated with cytotoxin K, hemolysin BL, non-hemolytic enterotoxin and enterotoxin FM, and an emetic syndrome, associated with the cereulide toxin. Owing to the heat resistance of and its ability to grow in milk, this organism should be considered potentially hazardous in dairy products.

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Due to the rapidly increasing resistance to conventional antibiotics, antimicrobial peptides are emerging as promising novel drug candidates. In this study, peptide fragments were obtained from yellowfin tuna muscle by simulated gastrointestinal digestion, and their antimicrobial activity towards Gram-positive and Gram-negative bacteria was investigated. In particular, the antimicrobial activity of both medium- and short-sized peptides was investigated by using two dedicated approaches.

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Hepatitis E is an emerging threat in industrialized countries. The foodborne transmission linked to consumption of pork and game meat is considered the main source of autochthonous infection. In Europe, small outbreaks have been reported linked to the consumption of pork liver sausages and wild boar meat.

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Article Synopsis
  • The study analyzed 124 S. Typhimurium and 89 S. 1,4,[5],12:i:- isolates for antimicrobial susceptibility and genetic markers, using methods like Kirby-Bauer disk-diffusion and PCR assays.
  • It was found that S. Typhimurium exhibited more variability in resistance profiles and molecular types compared to S. 1,4,[5],12:i:-, and that strains from irrigation water were more susceptible to antibiotics.
  • Notably, none of the plasmid-borne virulence genes were detected in S. 1,4,[5],12:i:-, while 37.9% of S. Typhimurium strains carried these genes, highlighting significant genetic
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Article Synopsis
  • Two-dimensional materials like MoS and WS show promise for applications in nanoelectronics and biomedicine.
  • Researchers focus on environmentally friendly methods to produce high-quality MoS nanosheets for use in experiments.
  • The study reveals the nanosheets have a cytotoxic effect on tumor cells but not on normal cells, and they exhibit antibacterial properties against dangerous Salmonella strains.
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Synopsis of recent research by authors named "Angela Michela Immacolata Montone"

  • Angela Michela Immacolata Montone's recent research encompasses a diverse range of topics, primarily focusing on food safety, antimicrobial resistance, and anti-inflammatory properties of natural compounds.
  • Her studies utilize advanced techniques such as genomic characterization and high-resolution mass spectrometry, highlighting the persistence of antimicrobial resistance in Salmonella species and the infection control potentials of natural substances like humic substances and Caulerpin.
  • The research further explores the application of bioactive compounds in food preservation, showcasing innovative methods for enhancing shelf life and nutritional value, particularly in meat products and fermented goods.