Identifying and managing patients with acute coronary conditions.

In 2004, the then National Institute for Clinical Excellence (NICE) published a technology-appraisal guideline on the treatment of patients with unstable angina (UA) or non-ST elevation myocardial infarction (NSTEMI). This article reports the results of a study in which triage and treatment for this patient group in one emergency department (ED) was assessed against this NICE guideline. The study found that patients were triaged by ED staff successfully but that there had been a lack of awareness of prognostic risk groupings and that compliance with guidelines on early antiplatelet therapy had not been ideal.

Ethics report on interspecies somatic cell nuclear transfer research.

This report considers whether research involving the creation of human-animal interspecies somatic cell nuclear transfer (iSCNT) embryos raises new ethical issues, and if so, whether it requires additional or special criteria and oversight distinct from research on human-animal chimeras.

New ISSCR guidelines underscore major principles for responsible translational stem cell research.

The International Society for Stem Cell Research (ISSCR) task force that developed new Guidelines for the Clinical Translation of Stem Cells discusses core principles that should guide the responsible transition of basic stem cell research into appropriate clinical applications.