Chitosan/poly-γ-glutamic acid crosslinked hydrogels: Characterization and application as bio-glues.

Ecofriendly hydrogels were prepared using chitosan (CH, 285 kDa) and two fractions of low molecular weight microbial poly-γ-glutamic acid (γ-PGA) (R1 and R2 of 59 kDa and 20 kDa, respectively). The hydrogels were synthesized through sustainable physical blending, employing three CH/γ-PGA mass ratios (1/9, 2/8, and 3/7), resulting in the formation of physically crosslinked materials. The six resulting CH/R1 and CH/R2 hydrogels were physico-chemically characterized and the ones with the highest yields (CH/R1 and CH/R2 ratio of 3/7), analyzed for rheological and morphological properties, showed to act as bio-glues on wood and aluminum compared to commercial vinyl- (V1) and acetovinyl (V2) glues.

Functional neurological disorder: a comparative analysis of experience of Czech, Slovak, and Italian neurologists.

Aim Of Study: We aimed to compare knowledge, opinions, and clinical experiences among Czech, Slovak, and Italian neurologists to identify potential educational gaps and unify understanding.

Clinical Rationale For Study: Functional neurological disorder (FND) is a disabling condition characterised by motor, sensory, or cognitive symptoms which are incompatible with other neurological disorders. Novel diagnostic and treatment approaches have improved FND management.

Physicochemical Characterization of Chitosan/Poly-γ-Glutamic Acid Glass-like Materials.

This paper sets up a new route for producing non-covalently crosslinked bio-composites by blending poly-γ-glutamic acid (γ-PGA) of microbial origin and chitosan (CH) through poly-electrolyte complexation under specific experimental conditions. CH and two different molecular weight γ-PGA fractions have been blended at different mass ratios (1/9, 2/8 and 3/7) under acidic pH. The developed materials seemed to behave like moldable hydrogels with a soft rubbery consistency.

Trait-related neural basis of attentional bias to emotions: a tDCS study.

Negative emotional stimuli can strongly bias attention, particularly in individuals with high levels of dispositional negative affect (NA). The current study investigated whether the prefrontal cortex (PFC), a brain region involved in the top-down regulation of emotional processing, plays a different role in controlling attention to emotions, depending on the individual NA. Sham and anodal transcranial direct current stimulation (tDCS) was delivered over the right or left PFC while assessing attentional bias (AB) to emotions (happy, angry, sad faces) in individuals with higher and lower trait NA.

Psychiatrists' attitudes towards functional neurological disorders: results from a national survey.

Introduction: Functional neurological disorder (FND) presents motor, sensory, and cognitive symptoms characterized by clinical signs incongruent with known neurological disease. Together with other health professionals, like neurologists, psychiatrists can play an essential role in diagnosing and managing these disorders. Hence, understanding their opinion and clinical experience with FND is of utmost importance to catch potential educational needs and improve healthcare services for patients.

Tuning the Morphology of HDPE/PP/PET Ternary Blends by Nanoparticles: A Simple Way to Improve the Performance of Mixed Recycled Plastics.

Due to a very low mixing entropy, most of the polymer pairs are immiscible. As a result, mixing polymers of different natures in a typical mechanical recycling process leads to materials with multiple interfaces and scarce interfacial adhesion and, consequently, with unacceptably low mechanical properties. Adding nanoparticles to multiphase polymeric matrices represents a viable route to mitigate this drawback of recycled plastics.

Curing Kinetics of Bioderived Furan-Based Epoxy Resins: Study on the Effect of the Epoxy Monomer/Hardener Ratio.

The potential of furan-based epoxy thermosets as a greener alternative to diglycidyl ether of Bisphenol A (DGEBA)-based resins has been demonstrated in recent literature. Therefore, a deep investigation of the curing behaviour of these systems may allow their use for industrial applications. In this work, the curing mechanism of 2,5-bis[(oxiran-2-ylmethoxy)methyl]furan (BOMF) with methyl nadic anhydride (MNA) in the presence of 2-methylimidazole as a catalyst is analyzed.

Functional neurological disorder and placebo and nocebo effects: shared mechanisms.

Functional neurological disorder (FND) is characterized by neurological symptoms that cannot be explained by a structural neurological cause. Among the different aetiological models that have been proposed for FND, of note is the Bayesian predictive coding model, which posits that perception relies on top-down cortical predictions (priors) to infer the source of incoming sensory information. This model can also apply to non-pathological experiences, such as placebo and nocebo effects, wherein sensory information is shaped by prior expectations and learning.

The impact of recurrent Covid-19 waves on patients with Functional Movement Disorders: A follow-up study.

Background: Functional Movement Disorders (FMDs) might exacerbate in stressful conditions. As the global health emergency due to Covid-19 rise and multiple waves hit the Italian population, the recurrent severe restrictions' periods imposed could represent important triggers and worsen the symptoms of FMDs. Through a follow-up study, we compare results on Motor Symptoms (MS), Non-Motor Symptoms (NMS), and Global Health Status (GHS) of two surveys, one referred to the first Covid-19 wave and the other to the third Covid-19 wave.

Attentional bias to emotions after prolonged endurance exercise is modulated by age.

Physical exercise has an impact in biasing attention to positive or negative emotional stimuli. While attentional shift to emotions varies with age, evidence is lacking on the effect of prolonged endurance exercise on age-related attentional bias to emotions. This study aims at filling this knowledge gap, by applying a dot-probe task to measure attentional bias to emotions before and after a half-marathon in healthy participants of different ages (age range 21-65 years).

Opinion, knowledge, and clinical experience with functional neurological disorders among Italian neurologists: results from an online survey.

Background: Functional neurological disorders (FND) are disabling medical conditions commonly seen in neurological practice. Neurologists play an essential role in managing FND, from establishing a diagnosis to coordination of multidisciplinary team-based treatment for patients. With this study, we investigated the knowledge and the clinical experience of Italian neurologists in managing patients with FND.

Bodily self-perception during voluntary actions: The causal contribution of premotor cortex and cerebellum.

Voluntary actions are accompanied by the experience of controlling one's own movements (sense of agency) and the feeling that the moving body part belongs to one's self (sense of body ownership). So far, agency and body ownership have been investigated separately, leaving the neural underpinnings of the relation between the two largely unexplored. The aim of this study was to explore the causal role of two multisensory brain regions, that is the premotor cortex (PMc) and the cerebellum, in agency and body ownership concurrently on the same behavioral task, i.

Chitosan/Zeolite Composite Aerogels for a Fast and Effective Removal of Both Anionic and Cationic Dyes from Water.

Organic dyes are extensively used in many industrial sectors, and their uncontrolled disposal into wastewaters raises serious concerns for environmental and human health. Due to the large variety of such pollutants, an effective remediation strategy should be characterized by a broad-spectrum efficacy. A promising strategy is represented by the combination of different adsorbent materials with complementary functionalities to develop composite materials that are expected to remove different contaminants.

Movement perception of the tonic vibration reflex is abnormal in functional limb weakness.

Introduction: We tested the hypothesis that functional limb weakness is associated with possible dysfunction of the central processing of proprioceptive information, by evaluating the amount of tonic vibration reflex (TVR) and the perception of the TVR movement.

Methods: The study sample was 20 patients with functional weakness of the lower and/or the upper limbs and 25 healthy controls; delivery of 92-Hz transcutaneous vibration of the biceps brachii tendon of the unrestrained arm stimulated predominantly the muscle spindle afferent and elicited elbow flexion (tonic vibration reflex, TVR). Blindfolded participants had to match the final position of the vibrated arm with their contralateral tracking arm.

Functional Neurological Disorders as Seen by a Cohort of General Practitioners in Northern Italy: Evidence From an Online Survey.

General practitioners (GPs) provide primary care and advise their patients on which diagnostic and therapeutic pathways they judge most appropriate. For patients with functional neurological disorders (FND), receiving a proper explanation of diagnosis by their GP from the very beginning may drastically improve prognosis. Novel approaches to the diagnosis and treatment of FND have important implications for effective management.

Voxel-based morphometry and task functional magnetic resonance imaging in essential tremor: evidence for a disrupted brain network.

The pathophysiology of essential tremor (ET) is controversial and might be further elucidated by advanced neuroimaging. Focusing on homogenous ET patients diagnosed according to the 2018 consensus criteria, this study aimed to: (1) investigate whether task functional MRI (fMRI) can identify networks of activated and deactivated brain areas, (2) characterize morphometric and functional modulations, relative to healthy controls (HC). Ten ET patients and ten HC underwent fMRI while performing two motor tasks with their upper limb: (1) maintaining a posture (both groups); (2) simulating tremor (HC only).

Proprioceptive drift is affected by the intermanual distance rather than the distance from the body's midline in the rubber hand illusion.

In the rubber hand illusion (RHI), simultaneous brush stroking of a subject's hidden hand and a visible rubber hand induces a transient illusion of the latter to "feel like it's my hand" and a proprioceptive drift of the hidden own hand toward the rubber hand. Recent accounts of the RHI have suggested that the illusion would only occur if weighting of conflicting sensory information and their subsequent integration results in a statistically plausible compromise. In three different experiments, we investigated the role of distance between the two hands as well as their proximity to the body's midline in influencing the occurrence of the illusion.

Hedonicity in functional motor disorders: a chemosensory study assessing taste.

The aim of this study was to explore hedonicity to basic tastes in patients with functional motor disorders (FMDs) that are often associated with impairment in emotional processing. We recruited 20 FMD patients and 24 healthy subjects, matched for age and sex. Subjects were asked to rate the hedonic sensation (i.

Thermal and Fire Behavior of a Bio-Based Epoxy/Silica Hybrid Cured with Methyl Nadic Anhydride.

Thermosetting polymers have been widely used in many industrial applications as adhesives, coatings and laminated materials, among others. Recently, bisphenol A (BPA) has been banned as raw material for polymeric products, due to its harmful impact on human health. On the other hand, the use of aromatic amines as curing agents confers excellent thermal, mechanical and flame retardant properties to the final product, although they are toxic and subject to governmental restrictions.

Attentional avoidance of emotions in functional movement disorders.

Objective: Emotional difficulties are common in functional movement disorders (FMD), yet their contribution to the disease remains unclear. We explored the potential role of emotional difficulties as risk and maintaining factors of FMD by looking at the effect of emotions on attention.

Method: The dot-probe task was used to investigate attentional biases induced by emotional faces in 25 patients with FMD and 25 healthy controls (HC).

Curing Behavior and Properties of Sustainable Furan-Based Epoxy/Anhydride Resins.

The last two decades have witnessed a significant growth in using bioderived materials, driven by the necessity of replacing fossil-derived precursors, reducing the fossil fuel consumption, and lowering the global environmental impact. This is possible thanks to the availability of abundant resources from biomasses and the development of optimized technologies based on the principles of sustainability and circular economy. Herein, we report on the synthesis and characterization of new carbohydrate-derived epoxy resins.

Effects of Probiotics on Cognitive Reactivity, Mood, and Sleep Quality.

Recent demonstration that probiotics administration has positive effects on mood state in healthy populations suggests its possible role as an adjunctive therapy for depression in clinical populations and as a non-invasive strategy to prevent depressive mood state in healthy individuals. The present study extends current knowledge on the beneficial effects of probiotics on psychological well-being, as measured by changes in mood (e.g.

Age-related changes in the sense of body ownership: New insights from the rubber hand illusion.

How do age-related changes affect the sense of body ownership? This study tackles this issue by means of the rubber hand illusion (RHI), a widely used experimental tool for investigating the sense of body ownership. There is ample literature on the RHI in young populations, but research on age-related changes in the RHI is still scarce. Here we extend the use of the RHI to examine the changes in the sense of body ownership related to healthy aging.