Publications by authors named "Angela Margherita Aura"

Article Synopsis
  • Surface plasmon resonance (SPR) has potential for molecular diagnostics but struggles with analyzing patient samples due to fouling by interfering species in biological fluids like blood plasma.
  • A new surface coating using a triethylene glycol (PEG(3))-pentrimer carboxybetaine system is proposed, which offers excellent antifouling properties at a thickness of less than 2 nm, making it suitable for sensitive SPR detection.
  • The study compares this new coating’s antifouling performance against other existing surface layers using pooled human plasma samples and demonstrates its application for detecting human arginase 1 in plasma through immunologic SPRI biosensing.
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