Flat Electroretinography and Acute Visual Loss After Ocriplasmin Injection for Vitreomacular Adhesion Complicating Macular Schisis.

A 53-year-old woman with macular and diffuse retinoschisis complicated by presumed vitreomacular traction underwent unilateral intravitreal ocriplasmin injection. Within hours after injection, she noted a loss of vision and the perception of "negative" images in the treated eye. Electrophysiologic testing revealed flat waveforms, and optical coherence tomography (OCT) showed initial decreased central macular thickness at day 1, followed by massive increased macular thickness with subfoveal neurosensory retinal detachment at 1 week.

Bilateral vasoproliferative retinal tumors in a patient with autosomal dominant aniridia.

Purpose: To document retinal vasoproliferative tumors in a patient with aniridia.

Methods: A 32-year-old woman with known autosomal dominant aniridia and lifelong visual acuity of approximately 20/80 noted further visual acuity loss.

Results: Examination revealed horizontal nystagmus and visual acuity of 20/100 in both eyes.

The International Classification of Retinoblastoma predicts chemoreduction success.

Purpose: To evaluate the reliability of the International Classification of Retinoblastoma (ICRB) for predicting treatment success with chemoreduction (CRD).

Design: Noncomparative interventional case series.

Participants: Two hundred forty-nine consecutive eyes.