Publications by authors named "Angela Dei Giudici"
Background: Despite mounting evidence, the impact of the interplay between weather and pollution features on the risk of acute cardiac and cerebrovascular events has not been entirely appraised. The aim of this study was to perform a comprehensive cluster analysis of weather and pollution features in a large metropolitan area, and their association with acute cardiac and cerebrovascular events.
Methods: Anonymized data on acute myocardial infarction (AMI) and acute cerebrovascular events were obtained from 3 tertiary care centers from a single large metropolitan area.
Article Synopsis
- Environmental factors and weather changes have a significant impact on the incidence of ST-elevation myocardial infarction (STEMI), a serious type of heart attack, though previous research on this connection is limited.
- In a study analyzing data from two large Italian urban areas, specific pollutants like carbon monoxide, nitrogen dioxide, and particulate matter were found to predict STEMI occurrences days in advance, suggesting a link between air quality and heart health.
- The findings highlight the potential for using environmental and weather data to predict STEMI risk, though the study does not establish direct causation between these factors and heart attacks.
Article Synopsis
- Initial studies showed that renal denervation (RDN) via radiofrequency ablation can effectively reduce blood pressure in patients with resistant hypertension, but the SYMPLICITY-HTN-3 trial did not find significant benefits compared to controls.
- New advancements like second-generation multi-electrode devices and ultrasound techniques have demonstrated promising results in more recent trials (SPYRAL HTN-ON MED, SPYRAL HTN-OFF MED, and RADIANCE-HTN SOLO) showing safety and efficacy for RDN.
- Despite these findings generating renewed interest in RDN for treating hypertension, further extensive and long-term studies are needed to establish its definitive role in treatment.
Background: The impact of seasonal changes on the incidence of acute myocardial infarction has been incompletely appraised, especially in the modern era of primary percutaneous coronary intervention (PPCI). We aimed to appraise the overall and season-specific impact of climate changes on the daily rate of PCCI.
Methods: Details on PPCI and climate changes were retrospectively collected in three high-volume Italian institutions with different geographical features.