Publications by authors named "Angela Cattani"
Article Synopsis
- - Current HIV vaccines aimed at boosting CD8 T cells haven't effectively controlled the virus after infection.
- - Research shows that the cytotoxic ability of vaccine-induced CD8 T cells is lower than in those who naturally control HIV, due to insufficient degranulation when facing low levels of antigens from infected cells.
- - The study indicates that the polyclonal nature of the vaccine-induced T cell receptor (TCR) repertoire limits their effectiveness, suggesting that better CD8 T cell responses might need vaccines that promote stronger clonal selection of TCRs.
