Publications by authors named "Angel S Angelov"
Schizophrenia (Heidelb)
December 2022
Article Synopsis
- - KarXT, a combination of xanomeline and trospium, showed effectiveness and tolerability in treating schizophrenia in the EMERGENT-1 study, hitting its primary and secondary goals while being well tolerated overall.
- - The study involved 179 patients who either received KarXT or a placebo, revealing that the majority of side effects (like nausea and dry mouth) were mild and temporary, with no participants dropping out due to these issues.
- - Additionally, KarXT did not significantly affect body weight, metabolic parameters, or vital signs, confirming its safety profile in relation to the muscarinic activity of its components.
