Prospective validation of a risk score to predict pacemaker implantation after transcatheter aortic valve replacement.

Introduction: The need for pacemaker is a common complication after transcatheter aortic valve replacement (TAVR). We previously described the Emory Risk Score (ERS) to predict the need for new pacemaker implant (PPM) after TAVR. Metrics included in the score are a history of syncope, pre-existing RBBB, QRS duration ≥140 ms, and prosthesis oversizing ≥16%.

Safety of same-day discharge after lead extraction procedures.

Background: Same-day discharge (SDD) after cardiovascular procedures is rapidly gaining ground.

Objective: We sought to evaluate the safety of SDD after transvenous lead extraction (TLE).

Methods: We performed a retrospective chart review of patients who underwent elective TLE between January 2020 and October 2021 at our institution.

The Feasibility and Safety of Flecainide Use Among Patients With Varying Degrees of Coronary Disease.

Background: Class IC antiarrhythmic agents are effective for treating atrial tachyarrhythmias, but their use is restricted in patients with coronary artery disease (CAD). Data on the safety of the use of IC agents in patients with CAD in the absence of recent acute coronary syndromes are lacking.

Objectives: This study sought to evaluate the safety and feasibility of treatment with IC agents in patients with varying degrees of CAD in a large serial, real-world cohort.

Same-Day Versus Next-Day Discharge Strategies for Left Atrial Ablation Procedures: A Parallel, Intra-Institutional Comparison of Safety and Feasibility.

Background: Head-to-head comparative data for the postoperative care of patients undergoing left atrial ablation procedures are lacking.

Objective: We sought to investigate complication and readmission rates between patients undergoing same-day (SD) or next-day (ND) discharges for ablative procedures in the left atrium, primarily atrial fibrillation (AF).

Methods: Two electrophysiology centers simultaneously perform left atrial ablations with differing discharge strategies.

Incidence of Cancer Treatment Induced Arrhythmia Associated with Immune Checkpoint Inhibitors.

Background: Cancer treatmentinduced arrhythmia (CTIA) is a well-recognized form of cardiotoxicity associated with chemotherapy. Immune checkpoint inhibitors (ICI) have been associated with important forms of cardiotoxicity, including myocarditis. However, the incidence of CTIA associated with ICI has not been well characterized.

Prospective evaluation of health status, quality of life and clinical outcomes following implantable defibrillator generator exchange.

Background: Little is known about health status and quality of life (QoL) after implantable cardioverter-defibrillator (ICD) generator exchange (GE).

Methods: We prospectively followed patients undergoing first-time ICD GE. Serial assessments of health status were performed by administering the 36-Item Short Form Survey (SF-36).

Life cycle management of Micra transcatheter pacing system: Data from a high-volume center.

Background: Data on the management of Micra transcatheter pacing system (TPS) at the time of an upgrade or during battery depletion is limited.

Objective: We sought to evaluate the management patterns of patients implanted with a Micra TPS during long-term follow-up.

Methods: We retrospectively identified patients who underwent Micra implantation from April 2014 to November 2019.

Relationship between device-detected burden and duration of atrial fibrillation and risk of ischemic stroke.

Background: Wider availability of continuous rhythm monitoring has made feasible the incorporation of metrics of atrial fibrillation (AF) burden and duration into the decision to initiate anticoagulation. However, the relationship between thresholds of burden and duration and underlying risk factors at which anticoagulation should be considered remains unclear.

Objective: The purpose of this study was to evaluate the relationships of these metrics with each other and the outcome of stroke/transient ischemic attack (TIA).

Sex-based differences in procedural complications associated with atrial fibrillation catheter ablation: A systematic review and meta-analysis.

Background: Women undergoing atrial fibrillation catheter ablation (AFCA) have higher rates of vascular complications and major bleeding. However, most studies have been underpowered to detect differences in rarer complications such as stroke/transient ischemic attack (TIA) and procedural mortality.

Methods: We performed a systematic review of databases (PubMed, World of Science, and Embase) to identify studies published since 2010 reporting AFCA complications by sex.

Ablation of manifest septal accessory pathways: a single-center experience.

Background: Ablation of septal accessory pathways (SAPs) is associated with an increased risk of heart block. Data on outcomes of SAP ablation in adults are limited.

Objectives: To describe outcomes of SAP ablation in our center.

Cardiac implantable electronic devices in patients with persistent left superior vena cava-A single center experience.

Background: There are limited data on cardiac implantable electronic device implantation (CIED) in patients with persistent left superior vena cava (PLSVC).

Objective: To describe the outcomes of implanting CIEDs with a focus on cardiac resynchronization therapy (CRT) in patients with PLSVC.

Methods: We identified all patients with a PLSVC that underwent CIED implantation from December 2008 until February 2019 at our institution by querying the electronic medical record (n = 34).

Outcomes of convergent atrial fibrillation ablation with continuous rhythm monitoring.

Background: Outcomes of catheter ablation for persistent atrial fibrillation (PeAF) are suboptimal. The convergent procedure (CP) may offer improved efficacy by combining endocardial and epicardial ablation.

Methods: We reviewed 113 consecutive patients undergoing the CP at our institution.

The Safety and Feasibility of Same-Day Discharge After Implantation of MICRA Transcatheter Leadless Pacemaker System.

Background: Data suggests that same day discharge after implantation of trans-venous pacemakers is safe and feasible. We sought to determine whether same day discharge was feasible and safe following implantation of Medtronic MICRA leadless pacemakers.

Methods: We retrospectively identified all patients undergoing MICRA placement at our institution between April 2014 to August 2018 (n=167).

Outcomes of Micra leadless pacemaker implantation with uninterrupted anticoagulation.

Background: Implantation of the MICRA Leadless pacemaker requires the use of a 27 French introducer, blunt delivery system and device fixation to the myocardium via nitinol tines. While prior studies have proven its safety, it is unclear whether performing this procedure with uninterrupted anticoagulation exposes patients to increased risks. We sought to investigate the feasibility and safety of continuing therapeutic anticoagulation during the periprocedural period.

Implantable Cardioverter-Defibrillator Placement for Primary Prevention in 2,346 Patients: Predictors of One-Year Survival.

Guidelines suggest that patients who receive implantable cardioverter-defibrillators (ICDs) for primary prevention should be expected to live more than one year after placement. However, tools for validating this prognosis are not sufficiently predictive. We sought to identify definitive predictors of one-year survival after ICD placement.

Incidence of Cancer Treatment-Induced Arrhythmia Associated With Novel Targeted Chemotherapeutic Agents.

Background The incidence of cancer treatment-induced arrhythmia ( CTIA ) associated with novel, targeted chemotherapeutic agents ( TCA s) has not been well described. Methods and Results We identified all patients treated at our institution from January 2010 to December 2015 with selected TCA s. We defined CTIA as any new arrhythmia diagnosis code within 6 months after treatment initiation.

Long-term performance of a pacing lead family: A single-center experience.

Background: The performance of Abbott/St. Jude Medical (Sylmar CA) Tendril pacing leads has not been well characterized.

Objective: We sought to assess the performance of Tendril leads as compared with that of different pacing leads.

Effect of defibrillation threshold testing on effectiveness of the subcutaneous implantable cardioverter defibrillator.

Background: Defibrillation threshold (DFT) testing is recommended with the subcutaneous implantable cardioverter defibrillator (SICD).

Objective: To describe first shock efficacy for appropriate SICD therapies stratified by the presence of implant DFT testing.

Methods: We reviewed all patients receiving SICDs at our institution and stratified them based on whether implant DFT testing was performed.

Predictors of Left Ventricular Remodeling After Myocardial Infarction in Patients With a Patent Infarct Related Coronary Artery After Percutaneous Coronary Intervention (from the Post-Myocardial Infarction Remodeling Prevention Therapy [PRomPT] Trial).

Left ventricular (LV) remodeling after myocardial infarction (MI) is a strong predictor of heart failure and mortality. The predictors of long-term remodeling after MI have been incompletely studied. We therefore examined the correlates of LV remodeling in patients with large ST-segment elevation myocardial infarction and a patent infarct artery after percutaneous 2coronary intervention (PCI) from the randomized Post-Myocardial Infarction Remodeling Prevention Therapy trial.

Magnetic resonance imaging safety in nonconditional pacemaker and defibrillator recipients: A meta-analysis and systematic review.

Background: Recommendations regarding performance of magnetic resonance imaging (MRI) in non-MRI conditional pacemaker and defibrillator recipients are evolving. Previous studies have suggested low adverse event rates with MRI in nonconditional cardiac implantable electronic device (CIED) recipients, but low power limits optimal characterization of risk.

Objective: The purpose of this study was to perform a systematic review and meta-analysis to characterize the clinical risk associated with MRI in CIED recipients in order to improve power.

Procedural outcomes and long-term survival associated with lead extraction in patients with abandoned leads.

Background: The decision to abandon or extract superfluous sterile leads is controversial.

Objective: The purpose of this study was to compare procedural outcomes and long-term survival of patients with and those without abandoned leads undergoing lead extraction (LE).

Methods: Retrospective review of all patients who had undergone transvenous LE at our institution from January 2007 to May 2016 was performed.