Dietary aflatoxin B1 and antimalarial-a lumefantrine/artesunate-therapy perturbs male rat reproductive function via pro-inflammatory and oxidative mechanisms.

We investigated the impact of Coartem™ (COA) and aflatoxin B1 (AFB) on rats' hypothalamus, epididymis, and testis. Male rats were randomly grouped (n = 5 rats) and treated: control group (corn oil), AFB (70 µg/kg), COA (5 mg/kg), COA + AFB (5 + 0.035 mg/kg) and COA + AFB (5 + 0.