Publications by authors named "Angel Nikolov"
Article Synopsis
- Evidence suggests that antibodies may help control tuberculosis (TB), but the details of how they work and their potential for therapeutic use are not well explored.
- The researchers created 52 variants of the Fc region of an antibody targeting the Mycobacterium tuberculosis capsule, aiming to enhance its ability to restrict the bacteria.
- Their findings indicate that some engineered antibodies can effectively engage neutrophils to fight the infection by boosting their survival and antimicrobial activity, highlighting the promise of these antibodies as potential TB treatments.
Bacillus thuringiensis has been extensively used for the biological control of insect pests. Nematicidal B. thuringiensis strains have also been identified; however, virulence factors of such strains are poorly investigated.
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