Publications by authors named "Angel Moya-Mitjans"

Article Synopsis
  • This study evaluated cardioneuroablation (CNA) as a treatment for syncope by analyzing outcomes in 77 patients over a median follow-up of 12 months, focusing on recurrence rates and complications.
  • Results showed that 33.8% of patients experienced a recurrence of syncope, with women at a higher risk, while older patients (over 50) had a lower risk; general anesthesia or deep sedation and more than 30 radiofrequency applications correlated with better outcomes.
  • The findings suggest that the effectiveness of CNA may be lower than previously believed, highlighting the need for careful consideration of patient factors and procedural details when assessing treatment success.
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Introduction And Objectives: We report the results of the 2023 Spanish catheter ablation registry.

Methods: Procedural data were collected and incorporated into the REDCap platform by all participating centers through a specific form.

Results: There were 104 participating centers in 2023 compared with 103 in 2022.

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Background: Current recommendations regarding the use of surgical left atrial appendage (LAA) closure to prevent thromboembolisms lack high-level evidence. Patients undergoing open-heart surgery often have several cardiovascular risk factors and a high occurrence of postoperative atrial fibrillation (AF)-with a high recurrence rate-and are thus at a high risk of stroke. Therefore, we hypothesized that concomitant LAA closure during open-heart surgery will reduce mid-term risk of stroke independently of preoperative AF status and CHADS-VASc score.

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Article Synopsis
  • A multicenter clinical trial called POWER FAST III is set to compare high-power short-duration (HPSD) radiofrequency ablation with standard techniques for treating atrial fibrillation (AF), aiming to reduce procedure time without sacrificing safety or effectiveness.
  • The study involves two groups: one using higher power settings (70 W and 9-10 seconds) and another using lower power (25-40 W), measuring atrial arrhythmia recurrence and the risk of esophageal damage.
  • Results are expected to potentially validate the HPSD approach, influencing future clinical practices for AF ablation procedures.
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Article Synopsis
  • The study compares patients with a single syncopal episode (SSE) and those with recurrent syncopal episodes (RSE) who also have complete bundle branch block (cBBB), focusing on arrhythmic risk and clinical outcomes.
  • Results show that both groups have similar risks for arrhythmic syncope and similar rates of diagnostic yield from electrophysiological studies and implantable cardiac monitors.
  • The findings suggest that there is no clinical reason to treat patients with SSE differently from those with RSE, as they experience comparable outcomes and risks.
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Objective: To analyze if there are sex-related differences in patients with unexplained syncope and bundle branch block (BBB).

Background: Despite increasing awareness that sex is a major determinant of the incidence, etiology, and the outcomes of different arrhythmias, no studies have examined differences in presentation and outcomes between men and women with syncope and BBB.

Methods: Cohort study of consecutive patients with unexplained syncope and BBB was included from January 2010 to January 2021 with a median follow-up time of 3.

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Introduction And Objectives: Risk stratification of ventricular arrhythmias in patients with repaired tetralogy of Fallot (rTOF) remains unresolved. We aimed to identify right ventricular (RV) electrophysiological parameters potentially associated with a higher risk of ventricular arrhythmias in patients with rTOF.

Methods: We included all consecutive patients with rTOF who underwent RV electroanatomical mapping at a single tertiary center.

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Background: Syncope in patients with mid-range left ventricular ejection fraction (LVEF) can be due to potentially serious arrhythmic causes. However, there is no clear consensus on the best way to manage these patients.

Objectives: The objectives of this study were to determine the causes of syncope and assess the diagnostic yield and safety of a stepwise workup protocol in this population.

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Objective: The use of implantable cardiac monitors (ICM) is highly useful in syncope workup. Latest-generation devices can detect asymptomatic episodes of atrial fibrillation. The main objective of this study was to determine the incidence of subclinical atrial fibrillation (AF) detected in a patient population undergoing prolonged electrocardiographic monitoring with an ICM for the etiological workup of syncope.

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Background: Severe aortic stenosis (AoS) is considered a primary cause of syncope. However, other mechanisms may be present in these patients and accurate diagnosis can have important clinical implications. The aim of this study is to assess the different etiologies of syncope in patients with severe AoS and the impact on prognosis of attaining a certain or highly probable diagnosis for the syncope.

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Aims: Reflex vasovagal syncope (VVS) is the most common cause of syncope and patients with recurrent episodes may severely impair quality of life (QoL). This pre-specified analysis evaluated whether the clinically significant reduction in syncope burden demonstrated by dual-chamber pacing with closed loop stimulation (DDD-CLS) reported in the SPAIN trial translates into improved QoL.

Methods And Results: Patients aged ≥40 years with ≥5 VVS episodes and cardioinhibitory response induced by head-up tilt testing were included.

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Background: Historically, the majority of insertable cardiac monitor (ICM) procedures were performed in the cardiac catheterization (cath) lab, electrophysiology (EP) lab, or operating room (OR). The miniaturization of ICMs allows the procedure to be relocated within the hospital without compromising patient safety. We sought to estimate the rate of untoward events associated with procedures performed within the hospital but outside the traditional settings and to characterize resource utilization, procedure time intervals, and physician experience.

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Article Synopsis
  • The study compares the effects of procainamide and flecainide on the His-Purkinje system during electrophysiological studies (EPS) in patients with syncope and bundle branch block (BBB).
  • Results show that flecainide leads to a greater increase in the His-ventricular interval and has a higher diagnostic yield than procainamide.
  • Patients who tested negative with flecainide had a lower need for pacemaker implantation compared to those who tested negative with procainamide.
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Background/objectives: Syncope in octogenarians represents an important problem in terms of comorbidity, quality of life and substantial medical costs, resulting from studies and treatments. An implantable loop ecorder (ILR) may improve diagnostic performance. The objective of the study was to evaluate the results of the ILR in a population of octogenarians.

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Article Synopsis
  • Patients with syncopal episodes and bundle branch block (BBB) are at risk of developing atrioventricular block (AVB), but identifying high-risk patients through electrophysiological study (EPS) often leads to false negatives.
  • The study involved 159 patients with syncope and BBB, showing that 24.8% needed pacemakers due to bradyarrhythmia during follow-up, with bifascicular block and HV intervals ≥60 ms being significant predictors.
  • An implantable loop recorder is a safe option for monitoring patients after negative EPS, and a risk score based on certain criteria can help identify those who may require further intervention, such as pacemaker implantation.
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Background: Radiofrequency ablation (RF) of ventricular tachycardia (VT) due to intramural foci has a high recurrence rate. Several techniques, such as bipolar ablation, irrigated needle ablation catheter, and retrograde coronary venous ethanol ablation have been suggested. Transarterial coronary ethanol ablation (TCEA) can also be effective.

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Article Synopsis
  • The study investigates predictors of positive electrophysiological study (EPS) results in patients who experience syncope and have bundle branch block (BBB).
  • It included 271 patients, observing that 41.7% had positive EPS results, with factors like conduction disturbance patterns and long PR intervals serving as significant predictors.
  • Patients with left bundle branch block (LBBB) or bifascicular block were associated with a higher likelihood of positive EPS, while clinical factors did not significantly impact the results.
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Article Synopsis
  • Intra-atrial re-entrant tachycardia (IART) is a serious issue for patients with congenital heart disease (CHD), predominantly stemming from cavotricuspid isthmus (CTI) problems, but non-CTI-related cases are also common due to heart damage.
  • The study included 94 CHD patients, revealing that 51% of IART cases were solely CTI-related, while 27.7% were only non-CTI-related, and 21.3% had both types.
  • Predictors for non-CTI-related IART include having a nontypical electrocardiogram (ECG) and a high complexity of CHD, with the latter showing
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Objectives: The aim of this study was to analyze the long-term outcomes after intra-atrial re-entrant tachycardia (IART) ablation in congenital heart disease (CHD).

Background: IART increases morbidity and mortality in CHD patients. Radiofrequency catheter ablation has evolved into the first-line treatment of this complication.

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Introduction And Objectives: To assess the diagnostic yield and cost-effectiveness of a diagnostic protocol based on the systematic use of latest-generation external loop recorders (ELRs) compared with the classic diagnostic strategy for patients with recurrent unexplained palpitations.

Methods: Two cohorts of consecutive patients referred for diagnosis of unexplained palpitations to the outpatient clinic of the arrhythmia unit were compared: a prospective cohort after the implementation of a new diagnostic protocol based on the systematic use of ELRs, and another, retrospective, cohort before the implementation of the protocol. The cost of diagnosis was calculated based on the number of complementary examinations, visits to outpatient clinics, or emergency department visits required to reach a diagnosis, and its costs according the prices published for the local health system.

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Background: Repeated implantable cardioverter-defibrillator (ICD) therapies cause myocardial damage and, thus, an increased risk of arrhythmias and mortality.

Hypothesis: Cardiac resynchronization therapy-defibrillator (CRT-D) reduces the number of appropriate therapies in patients with left ventricular dysfunction (left ventricular ejection fraction [LVEF] <50%).

Methods: The retrospective study involved 175 consecutive patients (mean age, 64.

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Background: Intra-atrial re-entrant tachycardia (IART) in patients with congenital heart disease (CHD) increases morbidity and mortality. Radiofrequency catheter ablation has evolved as the first-line treatment. The aim of this study was to analyze the acute success and to identify predictors of failed IART radiofrequency catheter ablation in CHD.

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