Publications by authors named "Angel Manuel Hidalgo-Ovejero"
The role of C-reactive protein as a risk marker of postoperative delirium in older hip fracture patients: a prospective cohort study.
Lucía Lozano-Vicario Ángel Javier Muñoz-Vázquez Bernardo Abel Cedeno-Veloz Román Romero-Ortuno Arkaitz Galbete Ángel Manuel Hidalgo-Ovejero
Eur Geriatr Med
December 2024
Purpose: Postoperative delirium (POD) is a common and serious neuropsychiatric syndrome that leads to higher morbidity and mortality. We investigated the association between serum C-reactive protein (CRP) and the occurrence of POD in older hip fracture patients, and whether CRP predicted POD better than a clinical model.
Methods: Patients aged ≥ 75 years admitted for surgical repair of an acute hip fracture were recruited.
Association of postoperative delirium with serum and cerebrospinal fluid proteomic profiles: a prospective cohort study in older hip fracture patients.
Lucía Lozano-Vicario Ángel Javier Muñoz-Vázquez Robinson Ramírez-Vélez Arkaitz Galbete-Jiménez Joaquín Fernández-Irigoyen Ángel Manuel Hidalgo-Ovejero
Geroscience
June 2024
Article Synopsis
- Postoperative delirium (POD) is a frequent issue in elderly patients after hip fracture surgery, leading to adverse outcomes, and this study aimed to find links between biomarkers and POD development.
- Sixty patients were observed for signs of POD after spinal anesthesia, using daily assessments to classify them into POD and non-POD groups, with blood and cerebrospinal fluid (CSF) samples collected for analysis.
- Results showed that 35% of patients developed POD, with a notable correlation between lower levels of the cytokine CXCL9 in both serum and CSF and the incidence of POD, suggesting that these biomarkers could help create predictive models for delirium.