Publications by authors named "Angel M Gil-Agudo"

Article Synopsis
  • Double-blind, randomized, placebo-controlled phase IIA trial tested the safety and pain relief efficacy of NFX-88 in chronic spinal cord injury (SCI) patients.
  • A total of 61 adults with varying levels of SCI participated, receiving either a placebo or one of three NFX-88 doses alongside pregabalin.
  • Results showed no severe side effects and indicated that the 2.1g/day dose of NFX-88 provided the most significant reduction in neuropathic pain, suggesting its potential for future trials.
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Spinal Cord Injury (SCI) refers to damage to the spinal cord that can affect different body functionalities. Recovery after SCI depends on multiple factors, being the rehabilitation therapy one of them. New approaches based on robot-assisted training offer the possibility to make training sessions longer and with a reproducible pattern of movements.

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Spinal cord injury (SCI) limits life expectancy and causes a restriction of patient's daily activities. In the last years, robotics exoskeletons have appeared as a promising rehabilitation and assistance tool for patients with motor limitations, as people that have suffered a SCI. The usability and clinical relevance of these robotics systems could be further enhanced by brain-machine interfaces (BMIs), as they can be used to foster patients' neuroplasticity.

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The purpose of this document is to establish practical recommendations on neurogenic bladder (NB) management based on scientific evidence and medical and nursing perspective in Spinal Cord Injury (SCI) Units as a first multidisciplinary consensual approach in Spain. METHODS: This paper reports results from the first modified Delphi consensus building exercise on this procedure. A committee of recognised opinion-leaders in rehabilitation and urology with special interest in NB was constituted.

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This pilot study proposed a method for assessing the status of vascular flow measured by transcutaneous oxygen pressure (TcPO2) in the area of the ischium in people with spinal cord injury (SCI). In a sample of 38 men (two groups: 12 physically active and 26 sedentary) with thoracic SCI, the distribution of the physiological response of the tissues under load during sitting was assessed through analysis of ischium TcPO2 values obtained by an oximeter. TcPO2 baseline, recovery time of TcPO2 after sitting (Trec), the percentage of TcPO2 (%TcPO2) of maximum pressure TcPO2, and mechanic maximal pressure (Pmax) were evaluated.

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The objective was to conduct a methodological pilot study to analyze wheelchair propulsion upper limb kinematics in standard competitive play considering the functional classification of each athlete. Ten basketball players with a functional classification ranging from 1 to 4 were included in the study. Four camcorders (Kinescan-IBV) and a treadmill for wheelchairs were used.

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