Do risk factors for persistent asthma modify lung function in infants and young children with recurrent wheeze?

Summary Background: There is very limited information on how the risk of persistent asthma in recurrent wheezing (RW) infants modifies their lung function early in life. The aim of this study is to compare lung function of RW infants and young children with a positive or negative asthma predictive index (API), an index previously used to anticipate asthma persistence into childhood and adolescence.

Methods: Two groups of RW infants and young children were recruited in two centres in Spain (Palma de Mallorca and Murcia).