[Incidence of gestational trophoblastic disease detected by routine histopathologic study of specimens obtained from abortions].

Background: Gestational trophoblastic disease (GTD) comprises different types of placental changes distinguished by histologic hydropic degeneration and swelling of chorionic villi.

Objective: To report incidence of gestational trophoblastic disease in a general hospital.

Material And Methods: A cross-sectional study in the period of January 2000 to June 2006 was made.

EcoRI polymorphism of the metastasis-suppressor gene NME1 in Mexican patients with breast cancer.

Human breast cancer cells with high metastatic potential show reduced expression of the metastasis-suppressor gene NME1. There are two polymorphic sites for the restriction enzymes BglII and EcoRI, both detectable by Southern blot analysis. Although the BglII site has been analyzed for loss of heterozygosity, the biallelic EcoRI site polymorphism has not been studied in association with breast cancer, complications or metastasis.

Identification of DNA sequences and viral proteins of 6 human papillomavirus types in retinoblastoma tissue.

Purpose: To detect DNA and proteins of human papillomavirus (HPV) in paraffin-embedded retinoblastoma (RB) tissue, to identify the viral types present and to describe a possible association between the presence of HPV and a particular form of RB.

Materials And Methods: Fifty-one samples from ocular tissues of RB patients and of six controls enucleated for non-neoplastic reasons were obtained and analyzed by Polymerase Chain Reaction (PCR) with consensus primers to detect HPV. Viral type identification was performed by Restriction Fragment Length Polymorphisms (RFLP) analysis.

[Squamous intra-epithelial lesions in HIV seropositive females. Their frequency and association with cervical neoplasia risk factors].

Objective: Determining the prevalence of squamous intraepithelial lesions (SIL), and their association with known cervical neoplasia risk factors in seropositive HIV female patients.

Materials And Methods: A transversal study including 50 seropositive HIV female patients was carried out. The patients were interrogated concerning known cervical neoplasia risk factors.